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Cell line · CVCL_0006

THP-1

Cancer cell line, Homo sapiens. Childhood acute monocytic leukemia. 579 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. THP-1. Cell lines, record CVCL_0006. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0006

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Cell line

As Cellosaurus gives it.

Name
THP-1
Accession
CVCL_0006
RRID
RRID:CVCL_0006
Synonyms
THP1, THP 1, THPI, THP-1(ATCC), THP-1-O, O-THP-1, Tohoku Hospital Pediatrics-1
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
1Y
Category
Cancer cell line
Diseases
Childhood acute monocytic leukemia (NCIt C9163); Acute monoblastic/monocytic leukemia (ORDO Orphanet_514)
Derived from
Peripheral blood (in situ)
Entry created
2012-04-04
Entry updated
2026-10-22

Source Cellosaurus

Problems1

ProblemCellosaurus's note
CautionNRAS mutation indicated incorrectly as being p.Gly12Ser in PubMed=9379676.

Source Cellosaurus

Papers579

2 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

PaperJournalYearHow we knowRetractedSource
PubMed 42999633Immunotargets Ther2026Its Methods give the RRID and name the linePubMed
BCLAF1 links RNA splicing to ATF4-dependent metabolic adaptation in acute myeloid leukemia.Sci Adv2026Its Methods give the RRID and name the linePubMed
Knockdown of a regulatory barcode shifts macrophage polarization destination from M1 to M2 and increases pathogen burden upon S. aureus infection.Elife2026Its Methods give the RRID and name the linePubMed
IL10RB-AS1 promotes pro-caspase-1-dependent pyroptosis via regulating the oligomerization and nucleation of CARD8 C-terminal domain to suppress acute myeloid leukemia.Cell Death Dis2026Its Methods give the RRID and name the linePubMed
Experimental and Pharmacoinformatic Studies Reveal Allium cepa L. Extract-Mediated Modulation of Hepatitis B Virus Associated Inflammatory Pathways via Quercetin Glucoside Derivatives.Chem Biodivers2026Its Methods give the RRID and name the linePubMed
Intestinal microbiota-associated LysoPC(16:0) promotes endometriosis via PPARγ-mediated M2 macrophage polarization and IL-10 secretion.iScience2026Its Methods give the RRID and name the linePubMed
Genetic-risk-informed integration of bulk and single-cell transcriptomes prioritizes ANPEP as a monocyte-associated candidate in aortic dissection.Front Cardiovasc Med2026Its Methods give the RRID and name the linePubMed
Extracellular vesicle-delivered siRNA targeting RCN1 suppresses acute myeloid leukemia through TFAM-dependent mtDNA-cGAS-STING signaling.Extracell Vesicles Circ Nucl Acids2026Its Methods give the RRID and name the linePubMed
O-GlcNAcylated TCF4 Drives Ferroptosis Resistance and Tumor-Associated Macrophage Infiltration to Promote Colorectal Cancer Liver Metastasis.Cancers (Basel)2026Its Methods give the RRID and name the linePubMed
CNPY3 variants associated with a recessive developmental and epileptic encephalopathy affect inflammasome and TLR function.EBioMedicine2026Its Methods give the RRID and name the linePubMed

1 to 10 of 579

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Relatives447

RelationCell lineAccessionProblemSource
Derived from itA-THP-1CVCL_5115Cell lines
Derived from itAbcam THP-1 AATF KOCVCL_B9W7Cell lines
Derived from itAbcam THP-1 ABCB1 KOCVCL_B9W8Cell lines
Derived from itAbcam THP-1 ABL1 KOCVCL_B9W9Cell lines
Derived from itAbcam THP-1 ACVR1B KOCVCL_B9WACell lines
Derived from itAbcam THP-1 ADGRG1 KOCVCL_B9WBCell lines
Derived from itAbcam THP-1 AGER KOCVCL_D2N2Cell lines
Derived from itAbcam THP-1 AGTR1 KOCVCL_B9WCCell lines
Derived from itAbcam THP-1 AHR KOCVCL_B9WDCell lines
Derived from itAbcam THP-1 AIM2 KOCVCL_B9WECell lines

1 to 10 of 447

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Cell banks25

Cell bankCatalog numberStatusSource
ATCCTIB-202ATCC
Abcamab271147Abcam
Abcamab275477Abcam
Abcamab281894Abcam
AddexBioC0003024/4956Cellosaurus
BCRC60430BCRC
BCRJ0234BCRJ
BEI_ResourcesARP-9942BEI_Resources
CCTCCGDC0100Cellosaurus
CLS300356CLS

1 to 10 of 25

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Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0006

GET https://conductscience.org/api/cell-lines/v1/CVCL_0006/papers?page=2

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