Cell line · CVCL_0007
U-937
Cancer cell line, Homo sapiens. Adult acute monocytic leukemia. Cellosaurus records it as partially contaminated. 154 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. U-937. Cell lines, record CVCL_0007. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0007
On this page
Cell line
As Cellosaurus gives it.
- Name
- U-937
- Accession
- CVCL_0007
- RRID
- RRID:CVCL_0007
- Synonyms
- U937, U 937
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 37Y
- Category
- Cancer cell line
- Diseases
- Adult acute monocytic leukemia (NCIt C8263); Acute monoblastic/monocytic leukemia (ORDO Orphanet_514)
- Derived from
- Pleural effusion (in situ)
- Entry created
- 2012-04-04
- Entry updated
- 2026-06-25
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Partially contaminated | Some ATCC stocks were cross-contaminated by K-562 initially (PubMed=7759961). The problem was corrected and subsequent stocks have been confirmed to carry only U-937. |
Source Cellosaurus
Papers154
1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| IL10RB-AS1 promotes pro-caspase-1-dependent pyroptosis via regulating the oligomerization and nucleation of CARD8 C-terminal domain to suppress acute myeloid leukemia. | Cell Death Dis | 2026 | Its Methods give the RRID and name the line | PubMed | |
| FDXR upregulation by p63/p73 is a prognostic and therapeutic marker of adult T-cell leukemia/lymphoma. | EMBO Mol Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Nicotinic Acid Restriction Potentiates NAMPT Inhibition in Acute Myeloid Leukemia Xenograft Models. | Cancer Res Commun | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Cross-Talk Between Histamine H2 Receptor and Glucocorticoid Receptor: Potential Implications in Acute Myeloid Leukemia Treatment. | Pharmacol Res Perspect | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Impact of IL-21 on CAR T-cell manufacturing: phenotypic, metabolic, and functional outcomes. | Front Immunol | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Bone marrow stromal cells promote chemoresistance in acute myeloid leukaemia through P2RX7-mediated antioxidant defence. | Exp Mol Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| MYDGF as a telomerase activator and therapeutic target for osteoarthritis. | Adv Biotechnol (Singap) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Novel noscapine derivative induces AML differentiation by dual-engaging DHODH and mitochondrial lipids to trigger a metabolic-epigenetic-transcriptional cascade. | Acta Pharm Sin B | 2026 | Its Methods give the RRID and name the line | PubMed | |
| M2 Macrophages Attenuate AQP2+ Collecting Duct Cell Apoptosis via the TRAF1-TRAF2 Complex to Suppress Randall's Plaque Formation. | Research (Wash D C) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| TP53-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition. | Sci Adv | 2026 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 154
See all 154 papersRelatives49
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Derived from it | EDITGENE U-937-CopGFP | CVCL_F6BN | Cell lines | |
| Derived from it | EDITGENE U-937-FLUC | CVCL_F5U4 | Cell lines | |
| Derived from it | EL 1 | CVCL_3680 | Has a recorded problem | Cell lines |
| Derived from it | HyCyte U-937 KO-hCRBN | CVCL_F1UW | Cell lines | |
| Derived from it | HyCyte U-937 KO-hIL1RAP | CVCL_F1UX | Cell lines | |
| Derived from it | HyCyte U-937 KO-hPTPRA | CVCL_E1N8 | Cell lines | |
| Derived from it | HyCyte U-937 stable cell line for hHIF1A overexpression | CVCL_F4MX | Cell lines | |
| Derived from it | HyCyte U-937 stable cell line for hIL1RAP overexpression | CVCL_F4M0 | Cell lines | |
| Derived from it | JOSK-I | CVCL_2082 | Has a recorded problem | Cell lines |
| Derived from it | JOSK-K | CVCL_8141 | Has a recorded problem | Cell lines |
1 to 10 of 49
See all 49 relativesCell banks21
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| ATCC | CRL-1593 | Discontinued | Cellosaurus |
| ATCC | CRL-1593.2 | ATCC | |
| AddexBio | C0003005/72 | Cellosaurus | |
| BCRC | 60435 | BCRC | |
| BCRJ | 0242 | BCRJ | |
| CCTCC | GDC0080 | Cellosaurus | |
| CLS | 300368 | CLS | |
| DSMZ | ACC-5 | DSMZ | |
| ECACC | 85011440 | ECACC | |
| EDITGENE | EDC00301 | EDITGENE |
1 to 10 of 21
See all 21 cell banksData dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_0007
GET https://conductscience.org/api/cell-lines/v1/CVCL_0007/papers?page=2