Cell line · CVCL_0014

RPMI-8226

Cancer cell line, Homo sapiens. Plasma cell myeloma. 151 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. RPMI-8226. Cell lines, record CVCL_0014. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0014

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Cell line

As Cellosaurus gives it.

Name: RPMI-8226
Accession: CVCL_0014
RRID: RRID:CVCL_0014
Synonyms: RPMI 8226, RPMI.8226, RPMI8226, RPMI no. 8226, RPMI no 8226, RPMI #8226, 8226, RPMI 8226/S, RPMI-8226S, RPMI8226/S, 8226/S, Roswell Park Memorial Institute 8226, GM02132, GM2132, GM 2132, GM02132C, Simpson
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 61Y
Category: Cancer cell line
Diseases: Plasma cell myeloma (NCIt C3242); Multiple myeloma (ORDO Orphanet_29073)
Derived from: Peripheral blood (in situ)
Cell type: Plasma cell
Secondary accessions: CVCL_7353
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers151

Paper	Journal	Year	How we know	Source
A role for eIF5A in translational control of stress-inducible proteins in multiple myeloma cell lines.	Mol Oncol	2026	Its Methods give the RRID and name the line	PubMed
Unc-51 like kinase 3 (ULK3) contributes to autophagy and cell survival in multiple myeloma.	Nat Commun	2026	Its Methods give the RRID and name the line	PubMed
APRIL-driven BCMA/TACI dual-targeted ligand-drug conjugates for selective and potent therapy of multiple myeloma.	Acta Pharm Sin B	2026	Its Methods give the RRID and name the line	PubMed
Carrier-Free Berberine/Nitidine Chloride Self-Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
TP53 mutation drives unique transcriptional and functional vulnerabilities independent of del(17p) in multiple myeloma.	iScience	2026	Its Methods give the RRID and name the line	PubMed
CD47 promotes myeloma cell growth through JAK-STAT3/MYC signalling and is targetable by ruxolitinib.	Br J Haematol	2026	Its Methods give the RRID and name the line	PubMed
Aryl Aldehyde-Anchored Small Molecules Recruit FBXO22 for Targeted Degradation of NSD2.	J Med Chem	2026	Its Methods give the RRID and name the line	PubMed
Integrated Genomic and Epigenomic Analysis Reveals Epigenetic Plasticity in Disease Progression and Multidrug Resistance in Multiple Myeloma.	Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
A fully human pan VL9 HLA-E TCRm antibody enables functional dissection of HLA-E biology and checkpoint signaling.	iScience	2026	Its Methods give the RRID and name the line	PubMed
Dynamic Switching of Apoptosis-Modulating Bim Heterodimers in Response to BH3 Mimetics in Xenograft Models of Hematologic Malignancies.	Mol Cancer Ther	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 151

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Relatives22

Relation	Cell line	Accession	Problem	Source
Derived from it	B6B11	CVCL_9V32		Cell lines
Derived from it	BPS Bioscience RPMI-8226 TNFRSF17 KO	CVCL_E8DP		Cell lines
Derived from it	COLO 677	CVCL_1862	Has a recorded problem	Cell lines
Derived from it	COLO 775	CVCL_1996	Has a recorded problem	Cell lines
Derived from it	HyCyte RPMI-8226-Luc	CVCL_E3IL		Cell lines
Derived from it	KR-12	CVCL_3732		Cell lines
Derived from it	Karyochi-2	CVCL_E2UR		Cell lines
Derived from it	Karyochi-5	CVCL_E2UU		Cell lines
Derived from it	RF-S1	CVCL_A6KD		Cell lines
Derived from it	RPMI-8226-B25	CVCL_E5J8		Cell lines

1 to 10 of 22

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Cell banks16

Cell bank	Catalog number	Source
ATCC	CCL-155	ATCC
ATCC	CRM-CCL-155	ATCC
AddexBio	C0003002/62	Cellosaurus
BCRC	60384	BCRC
CLS	300431	CLS
Coriell	GM02132	Coriell
DSMZ	ACC-402	DSMZ
ECACC	87012702	ECACC
IZSLER	BS TCL 92	Cellosaurus
JCRB	IFO50013	JCRB

1 to 10 of 16

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0014

GET https://conductscience.org/api/cell-lines/v1/CVCL_0014/papers?page=2

API reference For AI assistants