Cell line · CVCL_0019
SH-SY5Y
Cancer cell line, Homo sapiens. Neuroblastoma. Cellosaurus records it as partially contaminated. 329 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. SH-SY5Y. Cell lines, record CVCL_0019. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0019
On this page
Cell line
As Cellosaurus gives it.
- Name
- SH-SY5Y
- Accession
- CVCL_0019
- RRID
- RRID:CVCL_0019
- Synonyms
- SH-Sy5y, SHSY5Y, SHSY-5Y, SK-SH-SY5Y, SY5Y, SH-SY5Y Parental
- Species
- Homo sapiens (Human)
- Sex
- Female
- Age at sampling
- 4Y
- Category
- Cancer cell line
- Diseases
- Neuroblastoma (NCIt C3270); Neuroblastoma (ORDO Orphanet_635)
- Derived from
- Bone marrow (metastatic)
- Parent
- SK-N-SH (CVCL_0531)
- Entry created
- 2012-04-04
- Entry updated
- 2026-06-25
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Partially contaminated | Some laboratories that are redistributing this cell line are in fact redistributing a contaminated cell line of mouse origin (PubMed=25182563). |
Source Cellosaurus
Papers329
5 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| RAS inhibition limits oncogenic signaling and tumorigenesis in neuroblastoma regardless of RAS mutational status | Sci Rep | 2026 | Its Methods give the RRID and name the line | PubMed | |
| PubMed 43004984 | Yale J Biol Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| PubMed 43003807 | Nat Commun | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Neuroprotective Effect of Magnoflorine Through Inhibition of Caspase‐3‐Mediated Neuronal Apoptosis: In Silico to In Vitro Validation | J Biochem Mol Toxicol | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Protective Role of miR-432-5p Against Propofol-Induced Neurotoxicity Through Regulation of ITK in SH-SY5Y Cells. | J Biochem Mol Toxicol | 2026 | Its Methods give the RRID and name the line | PubMed | |
| CCR1 Antagonism by BX471 Attenuates Neuroinflammation and Apoptosis: Preliminary Findings From an In Vitro Model of Neuronal Injury. | Pharmacol Res Perspect | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Carbonic anhydrase inhibition rescues heart function in the Tg2576 Alzheimer's mouse model by ameliorating cardiac amyloid-β pathology and neurotrophic-signaling impairment. | bioRxiv | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Riluzole-Derived Benzo[d]thiazoles as CK1δ Inhibitors for Amyotrophic Lateral Sclerosis-Related Neurodegeneration. | ChemMedChem | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Chrysanthemum Morifolium-Derived Nanovesicles Reduce Lactate-Associated Histone Lactylation and Modulate Microglia-Mediated Neuroinflammation in Sepsis-Associated Encephalopathy. | Adv Sci (Weinh) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Exosomal let-7c-5p From AMI Patient Plasma Modulates Neuronal PANoptosis via ZBP1 In Vitro. | Cell Biochem Funct | 2026 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 329
See all 329 papersRelatives67
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Parent | SK-N-SH | CVCL_0531 | Cell lines | |
| Derived from it | Abcam SH-SY5Y DLG4 KO | CVCL_B0YJ | Cell lines | |
| Derived from it | Abcam SH-SY5Y EFNB2 KO | CVCL_B7VN | Cell lines | |
| Derived from it | Abcam SH-SY5Y LMOD1 KO | CVCL_B7VQ | Cell lines | |
| Derived from it | Abcam SH-SY5Y PDGFRA KO | CVCL_B0YH | Cell lines | |
| Derived from it | Abcam SH-SY5Y PDGFRB KO | CVCL_B0YI | Cell lines | |
| Derived from it | Abcam SH-SY5Y PINK1 KO | CVCL_B0YK | Cell lines | |
| Derived from it | Abcam SH-SY5Y PRKN KO | CVCL_B0N9 | Cell lines | |
| Derived from it | Abcam SH-SY5Y SNAP25 KO | CVCL_B7VP | Cell lines | |
| Derived from it | EDITGENE SH-SY5Y-CopGFP | CVCL_F6AS | Cell lines |
1 to 10 of 67
See all 67 relativesCell banks18
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| ATCC | CRL-2266 | ATCC | |
| Abcam | ab275475 | Abcam | |
| AddexBio | C0005004/63 | Cellosaurus | |
| BCRJ | 0223 | BCRJ | |
| CCTCC | GDC0210 | Cellosaurus | |
| CLS | 300154 | CLS | |
| CancerTools | 161932 | CancerTools | |
| DSMZ | ACC-209 | DSMZ | |
| ECACC | 94030304 | ECACC | |
| EDITGENE | EDC00297 | EDITGENE |
1 to 10 of 18
See all 18 cell banksData dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_0019
GET https://conductscience.org/api/cell-lines/v1/CVCL_0019/papers?page=2