Cell line · CVCL_0021
U-251MG
Cancer cell line, Homo sapiens. Astrocytoma. 213 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. U-251MG. Cell lines, record CVCL_0021. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0021
On this page
Cell line
As Cellosaurus gives it.
- Name
- U-251MG
- Accession
- CVCL_0021
- RRID
- RRID:CVCL_0021
- Synonyms
- U-251 MG, U-251-MG, U-251_MG, U251-MG, U251MG, U-251, U251, U251n, U251N, 251 MG, 251MG, 251 MG(6)
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 75Y
- Category
- Cancer cell line
- Diseases
- Astrocytoma (NCIt C60781); Astrocytoma (ORDO Orphanet_94)
- Derived from
- Brain, parietal lobe (in situ)
- Entry created
- 2012-04-04
- Entry updated
- 2026-06-25
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers213
2 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Pharmacokinetic Tuning Redirects β‐Lapachone From NQO1 Bioactivation to Vimentin‐Targeted Oxidation in Cancer | Adv Sci (Weinh) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl-2 and Mcl-1 blockade in preclinical glioblastoma models. | FEBS Open Bio | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Low-Density Lipoprotein Receptor-Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption. | Adv Sci (Weinh) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Genome-wide CRISPR screen identifies PKMYT1 inhibition as a synthetic lethal vulnerability in IDH1-mutant glioma. | Cancer Lett | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation. | Mol Oncol | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming. | Adv Sci (Weinh) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7-dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma. | Adv Sci (Weinh) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| CCND1 Stability Regulated by USP7 Deubiquitination Controls Glioma Radioresistance via Ferroptosis. | Anal Cell Pathol (Amst) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| TIMELESS promotes glioma stemness and malignancy through JAK-STAT3 pathway. | J Biol Chem | 2026 | Its Methods give the RRID and name the line | PubMed | |
| COPS7B Drives Malignant Progression of Glioblastoma Through Translational Upregulation of the Downstream Functional Effector CLU. | Int J Mol Sci | 2026 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 213
See all 213 papersRelatives44
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Derived from it | B2-17 | CVCL_2864 | Cell lines | |
| Derived from it | EDITGENE CNR1 Knockout U251 MG Cell Line | CVCL_F5BY | Cell lines | |
| Derived from it | EDITGENE S1PR1 Knockout U251 MG Cell Line | CVCL_F5C0 | Cell lines | |
| Derived from it | EDITGENE U251MG-CopGFP | CVCL_F6CF | Cell lines | |
| Derived from it | EDITGENE U251MG-FLUC | CVCL_F5UX | Cell lines | |
| Derived from it | HyCyte CT26 mKRAS_p.G12C_c.572G＞T cell line | CVCL_F4L0 | Cell lines | |
| Derived from it | HyCyte U-251MG KO-hC1QBP | CVCL_F4G1 | Cell lines | |
| Derived from it | HyCyte U-251MG KO-hELDR | CVCL_F1UN | Cell lines | |
| Derived from it | HyCyte U-251MG KO-hFADS1 | CVCL_F1UP | Cell lines | |
| Derived from it | HyCyte U-251MG KO-hNR3C1 | CVCL_F1UQ | Cell lines |
1 to 10 of 44
See all 44 relativesCell banks13
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| AddexBio | C0005029/5016 | Cellosaurus | |
| CCTCC | GDC0093 | Cellosaurus | |
| CLS | 300385 | CLS | |
| ECACC | 09063001 | ECACC | |
| EDITGENE | EDC00299 | EDITGENE | |
| Hysigen | TCH-C366 | Hysigen | |
| ICLC | HTL99014 | ICLC | |
| JCRB | IFO50288 | JCRB | |
| KCB | KCB 200965YJ | Cellosaurus | |
| Kerafast | EDK001 | Kerafast |
1 to 10 of 13
See all 13 cell banksData dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_0021
GET https://conductscience.org/api/cell-lines/v1/CVCL_0021/papers?page=2