Cell line · CVCL_0025

Caco-2

Cancer cell line, Homo sapiens. Colon adenocarcinoma. 267 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. Caco-2. Cell lines, record CVCL_0025. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0025

On this page

Cell line

As Cellosaurus gives it.

Name: Caco-2
Accession: CVCL_0025
RRID: RRID:CVCL_0025
Synonyms: CaCo-2, CACO-2, Caco 2, CACO 2, CACO2, CaCo2, CaCO2, Caco2, Caco-2/ATCC, Caco-II
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 72Y
Category: Cancer cell line
Diseases: Colon adenocarcinoma (NCIt C4349)
Derived from: Colon (in situ)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers267

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
Integrative genomics and experimental validation identify a mechanosensitive gene signature associated with colorectal cancer liver metastasis.	iScience	2026	Its Methods give the RRID and name the line	PubMed
Alcohol disrupts spatial coordination of autophagy-lysosome pathways to impair intestinal barrier integrity.	EBioMedicine	2026	Its Methods give the RRID and name the line	PubMed
Targeting O6-methylguanine-DNA Methyltransferase Deficiency in Preclinical Models of Extracranial Human Cancers with a Tumor-Selective DNA-Modifying Agent.	Mol Cancer Ther	2026	Its Methods give the RRID and name the line	PubMed
Avobenzone induces intestinal injury by targeting ATG14 and impairing mitophagy.	Cell Commun Signal	2026	Its Methods give the RRID and name the line	PubMed
Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Customizable host and viral transcript enrichment using CRISPR-Cas9 long-read sequencing for characterization of low-to-moderate abundance isoforms.	NAR Genom Bioinform	2026	Its Methods give the RRID and name the line	PubMed
Endogenous CRISPR-Based Removal of Tetracycline Resistance in Bifidobacterium animalis subsp. lactis Through a Safe-by-Design Approach.	Microb Biotechnol	2026	Its Methods give the RRID and name the line	PubMed
Calu-3 cells as novel efficient cell culture system for Borna disease virus 1 (BoDV-1).	Virus Res	2026	Its Methods give the RRID and name the line	PubMed
Microbial enzyme-responsive inulin nanoparticles for colon-targeted oral delivery of 5-ASA toward improved therapy of inflammatory bowel disease.	Theranostics	2026	Its Methods give the RRID and name the line	PubMed
Host cell entry and neutralisation sensitivity of H3N2 influenza A virus subclade K.	NPJ Vaccines	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 267

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Relatives47

Relation	Cell line	Accession	Source
Derived from it	Abcam Caco-2 ACE2 KO	CVCL_B0YL	Cell lines
Derived from it	Abcam Caco-2 BMP2 KO	CVCL_C0BL	Cell lines
Derived from it	Abcam Caco-2 TMPRSS2 KO	CVCL_C0BM	Cell lines
Derived from it	C2BBe1	CVCL_1096	Cell lines
Derived from it	C2BBe2	CVCL_Z582	Cell lines
Derived from it	Caco-2 Cu Pro-R	CVCL_YP11	Cell lines
Derived from it	Caco-2 CuSO4-R	CVCL_YP12	Cell lines
Derived from it	Caco-2 DUSP6 KO	CVCL_C0R8	Cell lines
Derived from it	Caco-2 EJ6	CVCL_C8A0	Cell lines
Derived from it	Caco-2 UNC45A KO	CVCL_D0R6	Cell lines

1 to 10 of 47

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Cell banks19

Cell bank	Catalog number	Status	Source
ATCC	HTB-37		ATCC
Abcam	ab275464	Discontinued	Cellosaurus
AddexBio	C0009009/29		Cellosaurus
BCRJ	0059		BCRJ
CCTCC	GDC0153		Cellosaurus
CLS	300137		CLS
DSMZ	ACC-169		DSMZ
ECACC	09042001		ECACC
ECACC	86010202		ECACC
EDITGENE	EDC00200		EDITGENE

1 to 10 of 19

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0025

GET https://conductscience.org/api/cell-lines/v1/CVCL_0025/papers?page=2

API reference For AI assistants