Cell line · CVCL_0027

Hep-G2

Cancer cell line, Homo sapiens. Hepatoblastoma. Cellosaurus records it as misclassified. 496 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. Hep-G2. Cell lines, record CVCL_0027. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0027

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Cell line

As Cellosaurus gives it.

Name: Hep-G2
Accession: CVCL_0027
RRID: RRID:CVCL_0027
Synonyms: HEP-G2, Hep G2, HEP G2, HepG2, HEPG2
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 15Y
Category: Cancer cell line
Diseases: Hepatoblastoma (NCIt C3728); Hepatoblastoma (ORDO Orphanet_449)
Derived from: Liver (in situ)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems1

Problem	Cellosaurus's note
Misclassified	Originally thought to be a hepatocellular carcinoma cell line but shown to be from an hepatoblastoma (PubMed=19751877).

Source Cellosaurus

Papers496

Paper	Journal	Year	How we know	Source
PEGylated Chrysin: In Vitro Biological Activity and Mechanistic Insights in HepG2 Cells.	J Biochem Mol Toxicol	2026	Its Methods give the RRID and name the line	PubMed
Essential Oils of Argyreia capitiformis (Poir.) Ooststr. and Argyreia nasirii D.F. Austin: Chemical Analysis and Biological Activities.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Previously Undescribed Esters and an Alkaloid From Trollius chinensis With Anti-Inflammatory and Cytotoxic Activities.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Quinoxaline-Triazole Hybrids: Exploring the Impact of Substituent Architecture on Cytotoxic Potency and Receptor Interaction.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Phytochemical Profiling and Anticancer Potential of Ipomoea hederifolia L. Root Extract: LC-MS Characterization and Molecular Docking Insights.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Exploring Chemical Diversity Alongside Antioxidant, Antimicrobial, Antiproliferative, Anti-Inflammatory, and Caenorhabditis elegans Locomotor Responses in Whole, Caps and Stipes of Suillus luteus and Agaricus bisporus.	Pharmaceuticals (Basel)	2026	Its Methods give the RRID and name the line	PubMed
HDAC Inhibitors Potentiate Doxorubicin Cytotoxicity in HepG2 Cells and Alter DNA-Repair- and p53-Associated Transcriptional Programs.	Int J Mol Sci	2026	Its Methods give the RRID and name the line	PubMed
Integrated Multi-Omics and Network Pharmacology Reveal the Targeted Alleviation of MASLD by Litchi Pericarp Oligomeric Polyphenols via Quercetin.	Antioxidants (Basel)	2026	Its Methods give the RRID and name the line	PubMed
FXR and Nrf2 Mediate the Effect of Carbon Ion Irradiation on Drug Transporter OATP1A2 in Cancer Cells.	Biology (Basel)	2026	Its Methods give the RRID and name the line	PubMed
Isolation, Taxonomic Assignment, and Multi-Assay Bioactivity Profiling of Sodaleptolyngbya sp. HX-01 From Paddy Soil in Hoa Xuan.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 496

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Relatives257

Relation	Cell line	Accession	Source
Derived from it	Abcam Hep-G2 ACE2 KO	CVCL_B0ZH	Cell lines
Derived from it	Abcam Hep-G2 APOE KO	CVCL_B7V5	Cell lines
Derived from it	Abcam Hep-G2 ARG1 KO	CVCL_B7V6	Cell lines
Derived from it	Abcam Hep-G2 ARRB2 KO	CVCL_B0ZI	Cell lines
Derived from it	Abcam Hep-G2 B2M KO	CVCL_B0ZJ	Cell lines
Derived from it	Abcam Hep-G2 CD63 KO	CVCL_B0ZK	Cell lines
Derived from it	Abcam Hep-G2 CTNNB1 KO	CVCL_B0ZL	Cell lines
Derived from it	Abcam Hep-G2 LRP6 KO	CVCL_B0ZM	Cell lines
Derived from it	Abcam Hep-G2 MTOR KO	CVCL_B0ZN	Cell lines
Derived from it	Abcam Hep-G2 NF2 KO	CVCL_B0ZP	Cell lines

1 to 10 of 257

See all 257 relatives

Cell banks25

Cell bank	Catalog number	Source
ATCC	HB-8065	ATCC
Abcam	ab257304	Abcam
Abcam	ab275467	Abcam
AddexBio	C0015002/46	Cellosaurus
BCRC	60025	BCRC
BCRJ	0103	BCRJ
CCTCC	GDC0024	Cellosaurus
CLS	300198	CLS
DSMZ	ACC-180	DSMZ
ECACC	85011430	ECACC

1 to 10 of 25

See all 25 cell banks

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

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GET https://conductscience.org/api/cell-lines/v1/CVCL_0027

GET https://conductscience.org/api/cell-lines/v1/CVCL_0027/papers?page=2

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