Cell line · CVCL_0038

HaCaT

Spontaneously immortalized cell line, Homo sapiens. 216 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. HaCaT. Cell lines, record CVCL_0038. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0038

On this page

Cell line

As Cellosaurus gives it.

Name: HaCaT
Accession: CVCL_0038
RRID: RRID:CVCL_0038
Synonyms: HaCAT, HACAT, Hacat
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 62Y
Category: Spontaneously immortalized cell line
Derived from: Back, skin, epidermis (in situ)
Cell type: Keratinocyte
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems1

Problem	Cellosaurus's note
Caution	Although HaCaT is distributed by a number of sources, the only official DKFZ-approved supplier is CLS.

Source Cellosaurus

Papers216

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
Stemonine Alleviates UVB-Induced Keratinocyte Senescence by Activating SIRT3.	J Biochem Mol Toxicol	2026	Its Methods give the RRID and name the line	PubMed
Crisaborole-Loaded Nanoemulsion for Atopic Dermatitis: Localized Dermal Delivery of a Phosphodiesterase-4 Inhibitor.	Pharmaceutics	2026	Its Methods give the RRID and name the line	PubMed
Temporal Regulation of UVA-Induced Ferroptosis-Associated Injury in Keratinocytes.	Int J Mol Sci	2026	Its Methods give the RRID and name the line	PubMed
Design of Potent, Non-Toxic Antimicrobial Agents Derived from the Frog Skin Peptide Raniseptin-PL Active Against Gram-Negative ESKAPE+ Pathogens.	Antibiotics (Basel)	2026	Its Methods give the RRID and name the line	PubMed
Bacteroides fragilis outer membrane vesicle mediates Pseudomonadota colonization by inducing autophagy on the skin.	iScience	2026	Its Methods give the RRID and name the line	PubMed
Fridericia chica standardized extract combined with tocotrienol-enriched fraction from Bixa orellana promotes gastric mucosal protection: in vitro combination selection and in vivo evaluation.	Pharm Biol	2026	Its Methods give the RRID and name the line	PubMed
Molecular Targets and Potential Mechanisms of Luteolin Against Cervical Carcinoma: Integrative Approach Combining Network Pharmacology, Molecular Docking, Molecular Dynamics Simulations, and In Vitro Validation.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Integrative Assessment of Teucrium Extracts: Phytochemical Profile, Nutritional-Mineral Composition, Biological Activities, and Toxicological Assessment In Vitro and In Vivo.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Trophoblast derived extracellular vesicles trigger secondary vesicle release from endometrial epithelial cells.	Cell Commun Signal	2026	Its Methods give the RRID and name the line	PubMed
Poly-L-Lactic Acid Attenuates Fibrotic Remodeling During Cutaneous Wound Healing.	Int J Mol Sci	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 216

See all 216 papers

Relatives45

Relation	Cell line	Accession	Source
Derived from it	EDITGENE ATF4 Knockout HACAT Cell Line	CVCL_F5C7	Cell lines
Derived from it	EDITGENE GCH1 Knockout HaCaT Cell Line	CVCL_F6J6	Cell lines
Derived from it	EDITGENE HIF1A Knockout HaCaT Cell Line	CVCL_F5FG	Cell lines
Derived from it	EDITGENE Hacat-Cas9	CVCL_F5QQ	Cell lines
Derived from it	EDITGENE Hacat-CopGFP	CVCL_F6A2	Cell lines
Derived from it	EDITGENE Hacat-FLUC	CVCL_F5SK	Cell lines
Derived from it	HC-R1	CVCL_F1BF	Cell lines
Derived from it	HaCaT A-5	CVCL_XK16	Cell lines
Derived from it	HaCaT BHLHE40 (-/-)	CVCL_HD65	Cell lines
Derived from it	HaCaT HSP70B'-GFP reporter	CVCL_FA29	Cell lines

1 to 10 of 45

See all 45 relatives

Cell banks10

Cell bank	Catalog number	Status	Source
AddexBio	T0020001/117		Cellosaurus
BCRJ	0341	Discontinued	Cellosaurus
CCTCC	GDC0106		Cellosaurus
CLS	300493		CLS
DSMZ	ACC-771	Discontinued	Cellosaurus
EDITGENE	EDC00187		EDITGENE
ICLC	HL14001	Discontinued	Cellosaurus
IZSLER	BS CL 168		Cellosaurus
KCB	KCB 200442YJ		Cellosaurus
Ubigene	YC-A018		Ubigene

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0038

GET https://conductscience.org/api/cell-lines/v1/CVCL_0038/papers?page=2

API reference For AI assistants