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Cell line · CVCL_0042

U2OS

Cancer cell line, Homo sapiens. Osteosarcoma. 443 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. U2OS. Cell lines, record CVCL_0042. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0042

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Cell line

As Cellosaurus gives it.

Name
U2OS
Accession
CVCL_0042
RRID
RRID:CVCL_0042
Synonyms
U-2 OS, U-2OS, U-2-OS, U2-OS, U20-S, U20S, 2T
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
15Y
Category
Cancer cell line
Diseases
Osteosarcoma (NCIt C9145); Osteosarcoma (ORDO Orphanet_668)
Derived from
Bone, tibia (in situ)
Secondary accessions
CVCL_L856
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers443

3 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

PaperJournalYearHow we knowRetractedSource
Targeting tankyrase scaffolding in the β-catenin destruction complex by PROTAC overcomes the limitation of catalytic inhibitors in colorectal cancer.Elife2026Its Methods give the RRID and name the linePubMed
Pathogenic autoantibodies targeting DNA repair proteins are shared by cancer patients and healthy children later diagnosed with cancer.Front Immunol2026Its Methods give the RRID and name the linePubMed
Targeting GPX4 and FSP1 to exploit ferroptotic vulnerability in Ewing sarcoma.Front Oncol2026Its Methods give the RRID and name the linePubMed
The ROCK1 PHC1 domain mediates recruitment to Rho activity zones and contractility signaling.Life Sci Alliance2026Its Methods give the RRID and name the linePubMed
Aberrant Accumulation of Cyclin D1 Rewires Glutamine Metabolism and Generates a Metabolic Vulnerability in Squamous Cell Carcinoma.Cancer Res2026Its Methods give the RRID and name the linePubMed
An inertial-based spiral device for separating rare tumor cells from liquid biopsies.Bioeng Transl Med2026Its Methods give the RRID and name the linePubMed
Intravenously deliverable oncolytic virus VET3-TGI favorably alters the tumor microenvironment.J Immunother Cancer2026Its Methods give the RRID and name the linePubMed
A guide to selecting high-performing antibodies for Netrin-1 (UniProt ID: O95631) for use in western blot and immunoprecipitation.F1000Res2026Its Methods give the RRID and name the linePubMed
Integrative proteomics defines FANCA as a multifunctional hub linking DNA repair to translation.iScience2026Its Methods give the RRID and name the linePubMed
USP5 acts as a proteolytic switch to control SDE2 function via UBL-directed cleavage.Nat Commun2026Its Methods give the RRID and name the linePubMed

1 to 10 of 443

See all 443 papers

Relatives393

RelationCell lineAccessionProblemSource
Derived from itAbcam U2OS ACO1 KOCVCL_B0YXCell lines
Derived from itAbcam U2OS ATF1 KOCVCL_E1GJCell lines
Derived from itAbcam U2OS CD40 KOCVCL_B0YYCell lines
Derived from itAbcam U2OS COL1A1 KOCVCL_C0BNCell lines
Derived from itAbcam U2OS DDX1 KOCVCL_E7RYCell lines
Derived from itAbcam U2OS EZHIP KOCVCL_C0BPCell lines
Derived from itAbcam U2OS FHL2 KOCVCL_B0YZCell lines
Derived from itAbcam U2OS GPR137 KOCVCL_E1GKCell lines
Derived from itAbcam U2OS HNRNPD KOCVCL_B0Z0Cell lines
Derived from itAbcam U2OS KDM4C KOCVCL_C0BQCell lines

1 to 10 of 393

See all 393 relatives

Cell banks15

Cell bankCatalog numberStatusSource
ABMT8293ABM
ATCCHTB-96ATCC
Abcamab263976Abcam
Abcamab279979Abcam
BCRC60187BCRC
BCRJ0304BCRJ
CLS300364CLS
DSMZACC-785DSMZ
ECACC92022711ECACC
EDITGENEEDC00117EDITGENE

1 to 10 of 15

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Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0042

GET https://conductscience.org/api/cell-lines/v1/CVCL_0042/papers?page=2

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