Cell line · CVCL_0058

HeLa S3

Cancer cell line, Homo sapiens. Human papillomavirus-related endocervical adenocarcinoma. 60 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. HeLa S3. Cell lines, record CVCL_0058. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0058

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Cell line

As Cellosaurus gives it.

Name: HeLa S3
Accession: CVCL_0058
RRID: RRID:CVCL_0058
Synonyms: HeLa s3, HeLa-S3, HELA-S3, HeLa/S3, HeLa.S3, HeLa S 3, HeLa S-3, HeLaS3, HeLa, S3 clone, S3-HeLa, S3 HeLa
Species: Homo sapiens (Human)
Sex: Female
Age at sampling: 30Y6M
Category: Cancer cell line
Diseases: Human papillomavirus-related endocervical adenocarcinoma (NCIt C27677)
Derived from: Uterus, cervix (in situ)
Parent: HeLa (CVCL_0030)
Entry created: 2012-04-04
Entry updated: 2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers60

24 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

Paper	Journal	Year	How we know	Source
Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation.	Elife	2026	Its Methods give the RRID and name the line	PubMed
Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation.	bioRxiv	2025	Its Methods give the RRID and name the line	PubMed
Selective Depletion of Cancer Cells with Extrachromosomal DNA via Lentiviral Infection.	Cancer Res Commun	2025	Its Methods give the RRID and name the line	PubMed
Highly specific Immunoproteasome inhibitor M3258 induces proteotoxic stress and apoptosis in KMT2A::AFF1 driven acute lymphoblastic leukemia.	Sci Rep	2025	Its Methods give the RRID and name the line	PubMed
Annexin A5 controls VDAC1-dependent mitochondrial Ca2+ homeostasis and determines cellular susceptibility to apoptosis.	EMBO J	2025	Its Methods give the RRID and name the line	PubMed
Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders.	iScience	2024	Its Methods give the RRID and name the line	PubMed
A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy.	J Cell Biol	2024	Its Methods give the RRID and name the line	PubMed
A highly optimized human in vitro translation system.	Cell Rep Methods	2024	Its Methods give the RRID and name the line	PubMed
Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites.	Cell Genom	2024	Its Methods give the RRID and name the line	PubMed
Combinatorial regulation by ERK1/2 and CK1δ protein kinases leads to HIF-1α association with microtubules and facilitates its symmetrical distribution during mitosis.	Cell Mol Life Sci	2024	Its Methods give the RRID and name the line	PubMed

1 to 10 of 60

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Relatives55

Relation	Cell line	Accession	Source
Parent	HeLa	CVCL_0030	Cell lines
Derived from it	(HeLa S3) + p40PX-EGFP	CVCL_F4CF	Cell lines
Derived from it	GM10321	CVCL_1R87	Cell lines
Derived from it	HeLa 292	CVCL_WH96	Cell lines
Derived from it	HeLa BU-25	CVCL_2320	Cell lines
Derived from it	HeLa EGFP-654	CVCL_VS42	Cell lines
Derived from it	HeLa MR	CVCL_WH97	Cell lines
Derived from it	HeLa PurRII7	CVCL_4W41	Cell lines
Derived from it	HeLa S3 (sc)	CVCL_2934	Cell lines
Derived from it	HeLa S3 9IV	CVCL_ZM48	Cell lines

1 to 10 of 55

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Cell banks17

Cell bank	Catalog number	Status	Source
ATCC	CCL-2.2		ATCC
ATCC	CRL-7924	Discontinued	Cellosaurus
BCRC	60101		BCRC
CCTCC	GDC0193		Cellosaurus
CLS	300384		CLS
DSMZ	ACC-161		DSMZ
ECACC	87110901		ECACC
ICLC	HTL95020		ICLC
IZSLER	BS TCL 22		Cellosaurus
JCRB	IFO50011		JCRB

1 to 10 of 17

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

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CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0058

GET https://conductscience.org/api/cell-lines/v1/CVCL_0058/papers?page=2

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