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Cell line · CVCL_0093

RS4;11

Cancer cell line, Homo sapiens. Adult B acute lymphoblastic leukemia. 53 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. RS4;11. Cell lines, record CVCL_0093. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0093

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Cell line

As Cellosaurus gives it.

Name
RS4;11
Accession
CVCL_0093
RRID
RRID:CVCL_0093
Synonyms
RS4-11, RS4:11, RS 4;11, RS(4;11), RS411
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
32Y
Category
Cancer cell line
Diseases
Adult B acute lymphoblastic leukemia (NCIt C9143); B acute lymphoblastic leukemia with t(v;11q23.3) MLL rearranged (NCIt C80342); B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) (ORDO Orphanet_585918)
Derived from
Bone marrow (in situ)
Entry created
2012-04-04
Entry updated
2025-08-14

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers53

PaperJournalYearHow we knowRetractedSource
Development of CAR T Cells Targeting a Surface RNA-Binding Protein for the Treatment of Acute Leukemias.Cancer Discov2026Its Methods give the RRID and name the linePubMed
BCR::ABL1-Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B-ALL Cells to Enhancer-Targeting Drugs.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia.EMBO J2026Its Methods give the RRID and name the linePubMed
Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
Highly specific Immunoproteasome inhibitor M3258 induces proteotoxic stress and apoptosis in KMT2A::AFF1 driven acute lymphoblastic leukemia.Sci Rep2025Its Methods give the RRID and name the linePubMed
GREM1 deficiency induced bone marrow adipose niche promotes B-cell acute lymphoblastic leukemia disease progression.Int J Cancer2025Its Methods give the RRID and name the linePubMed
PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway-Deficient Acute Myeloid Leukemia.Cancer Res Commun2025Its Methods give the RRID and name the linePubMed
KMT2A degradation is observed in decitabine-responsive acute lymphoblastic leukemia cells.Mol Oncol2025Its Methods give the RRID and name the linePubMed
Novel immunotherapeutics against LGR5 to target multiple cancer types.EMBO Mol Med2024Its Methods give the RRID and name the linePubMed
Comparable efficacy of oral bendamustine versus intravenous administration in treating hematologic malignancies.Cancer Chemother Pharmacol2024Its Methods give the RRID and name the linePubMed

1 to 10 of 53

See all 53 papers

Relatives3

RelationCell lineAccessionProblemSource
Derived from itRS4;11 BCL2-F104LCVCL_XZ61Cell lines
Derived from itRS4;11 BCL2-G101VCVCL_XZ62Cell lines
Derived from itRS4;11 mouse MCL1CVCL_E8JJCell lines

Cell banks4

Cell bankCatalog numberStatusSource
ATCCCRL-1873ATCC
AddexBioC0003012/4671Cellosaurus
CLS305360CLS
DSMZACC-508DSMZ

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0093

GET https://conductscience.org/api/cell-lines/v1/CVCL_0093/papers?page=2