Cell line · CVCL_0105

DU145

Cancer cell line, Homo sapiens. Prostate carcinoma. 293 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. DU145. Cell lines, record CVCL_0105. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0105

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Cell line

As Cellosaurus gives it.

Name: DU145
Accession: CVCL_0105
RRID: RRID:CVCL_0105
Synonyms: DU-145, Du-145, DU 145, DU_145, DU.145, Duke University 145
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 69Y
Category: Cancer cell line
Diseases: Prostate carcinoma (NCIt C4863)
Derived from: Brain (metastatic)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers293

Paper	Journal	Year	How we know	Source
The VCPIP1-UBE3A Deubiquitination-Ubiquitination Cascade Contributes to Castration-Resistant Prostate Cancer Progression.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Primary tumor-derived lactate primes prostate cancer cells for a dormant fate.	Sci Adv	2026	Its Methods give the RRID and name the line	PubMed
A Graphene Oxide-Doped CuMOF Nanoplatform Enhances Chemodynamic Therapy and Suppresses CYP2J2-Mediated Linoleic Acid Metabolism in Castration-Resistant Prostate Cancer.	Int J Nanomedicine	2026	Its Methods give the RRID and name the line	PubMed
Combination of PARP inhibitor olaparib and a vascular disrupting agent reduces tumor growth in a preclinical model of prostate cancer.	Cancer Chemother Pharmacol	2026	Its Methods give the RRID and name the line	PubMed
Antitumor Activity of Combined Topoisomerase Inhibition and FLASH Radiotherapy in Head and Neck Carcinoma Biomodels.	MedComm (2020)	2026	Its Methods give the RRID and name the line	PubMed
Castration-resistant prostate cancer cells are addicted to the high activity of cyclin-dependent kinase 2.	Mol Oncol	2026	Its Methods give the RRID and name the line	PubMed
Vitronectin Enrichment in Prostate Cancer Liver Metastases Promotes Adhesion and Survival.	Cancer Res Commun	2026	Its Methods give the RRID and name the line	PubMed
MYDGF as a telomerase activator and therapeutic target for osteoarthritis.	Adv Biotechnol (Singap)	2026	Its Methods give the RRID and name the line	PubMed
Sodium Channel Blockers Demonstrate Binding Affinity for the Tandem Tudor Domain of the Epigenetic Hub UHRF1.	ChemMedChem	2026	Its Methods give the RRID and name the line	PubMed
A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer.	Cancer Cell	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 293

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Relatives20

Relation	Cell line	Accession	Problem	Source
Derived from it	BM-1604	CVCL_1968	Has a recorded problem	Cell lines
Derived from it	DU-145 R	CVCL_4Y36		Cell lines
Derived from it	DU-145-Luc	CVCL_J251		Cell lines
Derived from it	DU145 fat-1	CVCL_E6ZG		Cell lines
Derived from it	DU145-AR	CVCL_VE02		Cell lines
Derived from it	DU145-Cas9-539	CVCL_A9CI		Cell lines
Derived from it	DU145-Cas9-540	CVCL_A9CJ		Cell lines
Derived from it	DU145-Cas9-541	CVCL_A9CK		Cell lines
Derived from it	DU145-R	CVCL_C0QR		Cell lines
Derived from it	DU145-TxR	CVCL_ZX03		Cell lines

1 to 10 of 20

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Cell banks15

Cell bank	Catalog number	Source
ATCC	HTB-81	ATCC
AddexBio	C0019004/4984	Cellosaurus
BCRC	60348	BCRC
BCRJ	0078	BCRJ
CLS	300168	CLS
DSMZ	ACC-261	DSMZ
Hysigen	TCH-C170	Hysigen
ICLC	HTL99013	ICLC
IZSLER	BS TCL 141	Cellosaurus
KCB	KCB 200701YJ	Cellosaurus

1 to 10 of 15

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0105

GET https://conductscience.org/api/cell-lines/v1/CVCL_0105/papers?page=2

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