Cell line · CVCL_0123

3T3-L1

Spontaneously immortalized cell line, Mus musculus. 88 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. 3T3-L1. Cell lines, record CVCL_0123. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0123

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Cell line

As Cellosaurus gives it.

Name: 3T3-L1
Accession: CVCL_0123
RRID: RRID:CVCL_0123
Synonyms: 3T3 L1, 3T3L1, 3T3-L1 ad, NIH-3T3-L1, NIH3T3-L1
Species: Mus musculus (Mouse)
Sex: Male
Age at sampling: Embryo
Category: Spontaneously immortalized cell line
Derived from: Whole embryo (in situ)
Cell type: Fibroblast
Parent: 3T3-Swiss albino (CVCL_0120)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers88

2 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

Paper	Journal	Year	How we know	Source
ITGBL1 inhibits obesity and osteoporosis by maintaining adipogenic and osteogenic differentiation balance via the NEDD4-PPARγ-RUNX2 axis.	Cell Death Dis	2026	Its Methods give the RRID and name the line	PubMed
Persistent effects of pre-differentiation manganese exposure on adipogenesis and metabolic function in differentiated 3T3-L1 adipocyte cells.	J Hazard Mater Adv	2026	Its Methods give the RRID and name the line	PubMed
A stromal β-defensin, DEFB124, contributes to cutaneous host defense against Staphylococcus aureus.	iScience	2026	Its Methods give the RRID and name the line	PubMed
Tumor-Secreted ADAMTSL4 Activates Latent TGFβ1 to Drive Cancer Cachexia.	Cancer Discov	2026	Its Methods give the RRID and name the line	PubMed
Surface protein profiling reveals depot-specific features of subcutaneous and visceral adipose progenitor cells.	Biochem Biophys Rep	2026	Its Methods give the RRID and name the line	PubMed
The Fabrication of Protein Carriers for Intracellular Delivery of Antibiotics Against Intracellular Bacterial Infection.	Molecules	2026	Its Methods give the RRID and name the line	PubMed
Moderate iron restriction improves metabolism via epigenetic regulation of GDF15.	J Nutr Biochem	2026	Its Methods give the RRID and name the line	PubMed
Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows regeneration via mitochondrial uncoupling.	Cell Rep Med	2026	Its Methods give the RRID and name the line	PubMed
Adipocyte-specific FFA2 deletion leads to increased adipose inflammation and is associated with altered intestinal lipid handling in mice.	Physiol Rep	2026	Its Methods give the RRID and name the line	PubMed
Analysis of catabolic products of L-arginine; L-ornithine and L-citrulline and the residual L-arginine using the HPLC and LC-MS.	PLoS One	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 88

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Relatives16

Relation	Cell line	Accession	Source
Parent	3T3-Swiss albino	CVCL_0120	Cell lines
Derived from it	3T3-L1 CAR SNRK KO	CVCL_D4DA	Cell lines
Derived from it	3T3-L1 EGFP-ATA2	CVCL_QZ17	Cell lines
Derived from it	3T3-L1 MBX	CVCL_0A20	Cell lines
Derived from it	3T3-L1-GLUT4myc	CVCL_E6YT	Cell lines
Derived from it	3T3F442A	CVCL_0122	Cell lines
Derived from it	EDITGENE 3T3-L1-Cas9	CVCL_F5Q9	Cell lines
Derived from it	EDITGENE 3T3-L1-CopGFP	CVCL_F6A5	Cell lines
Derived from it	EDITGENE 3T3-L1-FLUC	CVCL_F5SN	Cell lines
Derived from it	EDITGENE Chchd10 Knockout 3T3-L1 Cell Line	CVCL_F6K2	Cell lines

1 to 10 of 16

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Cell banks17

Cell bank	Catalog number	Status	Source
ATCC	CCL-92.1	Discontinued	Cellosaurus
ATCC	CL-173		ATCC
AddexBio	P0011002/407		Cellosaurus
BCRC	60159		BCRC
BCRJ	0019		BCRJ
CCTCC	GDC0180		Cellosaurus
CLS	400107		CLS
ECACC	86052701		ECACC
EDITGENE	EDC00191		EDITGENE
Hysigen	TCM-C702		Hysigen

1 to 10 of 17

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0123

GET https://conductscience.org/api/cell-lines/v1/CVCL_0123/papers?page=2

API reference For AI assistants