Cell line · CVCL_0132

A-375

Cancer cell line, Homo sapiens. Amelanotic melanoma. 251 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. A-375. Cell lines, record CVCL_0132. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0132

On this page

Cell line

As Cellosaurus gives it.

Name: A-375
Accession: CVCL_0132
RRID: RRID:CVCL_0132
Synonyms: A 375, A375, A375-MEL, A375-mel, A375mel, 375
Species: Homo sapiens (Human)
Sex: Female
Age at sampling: 54Y
Category: Cancer cell line
Diseases: Amelanotic melanoma (NCIt C3802)
Derived from: Leg, skin (in situ)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers251

Paper	Journal	Year	How we know	Source
Integrative Assessment of Teucrium Extracts: Phytochemical Profile, Nutritional-Mineral Composition, Biological Activities, and Toxicological Assessment In Vitro and In Vivo.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Cullin-5 RING E3 ligase limits CD8⁺ T-cell persistence and effector responses during chronic antigen stimulation.	Cancer Immunol Res	2026	Its Methods give the RRID and name the line	PubMed
Genotype-driven tumor ecosystems drive immune evasion and immunotherapy resistance in melanoma.	Mol Cancer	2026	Its Methods give the RRID and name the line	PubMed
Computational design of optimized and preferentially paired human TCR constant regions for improved T cell function.	Sci Adv	2026	Its Methods give the RRID and name the line	PubMed
ImmTACs overcome cytotoxic T cell suppression.	Immunother Adv	2026	Its Methods give the RRID and name the line	PubMed
Flavasperfurans A and B, Two New Asperfuran Derivatives From the Marine-Derived Fungus Aspergillus flavus.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Chemical Constituents of the Deep-Sea-Derived Fungus Talaromyces wortmannii and Their Ferroptosis Inhibitory Activity.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Transient histone deacetylase inhibition reveals cell type invariant and specific effects of chromatin decondensation on irradiation response.	Front Cell Dev Biol	2026	Its Methods give the RRID and name the line	PubMed
Acquired Resistance to the PRMT5 Inhibitor Confers Collateral Sensitivity to MEK Inhibition in MTAP-Null Non-Small Cell Lung Cancer.	Biomolecules	2026	Its Methods give the RRID and name the line	PubMed
AI-enabled discovery and biochemical optimization of minibinders targeting cancer cell-surface proteins.	Nat Commun	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 251

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Relatives68

Relation	Cell line	Accession	Problem	Source
Derived from it	4-1.10	CVCL_6546		Cell lines
Derived from it	A-375 FOS-KO	CVCL_F4XG		Cell lines
Derived from it	A-375 Human CD228	CVCL_E8SQ		Cell lines
Derived from it	A-375 Human CLDN18.2	CVCL_E8SR		Cell lines
Derived from it	A-375 Human EGFR vIII	CVCL_XZ66	Has a recorded problem	Cell lines
Derived from it	A-375 KRAS p.G13D	CVCL_UD29		Cell lines
Derived from it	A-375 MEK1 p.Q56P	CVCL_UD28		Cell lines
Derived from it	A-375 NRAS p.Q61K	CVCL_JF22		Cell lines
Derived from it	A-375-Luc	CVCL_C8WV		Cell lines
Derived from it	A375 NRAS (Q61K/+/+)	CVCL_LC86		Cell lines

1 to 10 of 68

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Cell banks17

Cell bank	Catalog number	Status	Source
ATCC	CRL-1619		ATCC
ATCC	CRL-7904	Discontinued	Cellosaurus
Abcam	ab275461		Abcam
AddexBio	C0020004/4992		Cellosaurus
BCRC	60039		BCRC
BCRJ	0278		BCRJ
CCTCC	GDC0285		Cellosaurus
CCTCC	GDC0314		Cellosaurus
CLS	300110		CLS
ECACC	88113005		ECACC

1 to 10 of 17

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0132

GET https://conductscience.org/api/cell-lines/v1/CVCL_0132/papers?page=2

API reference For AI assistants