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Cell line · CVCL_0145

ARPE-19

Spontaneously immortalized cell line, Homo sapiens. 69 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. ARPE-19. Cell lines, record CVCL_0145. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0145

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Cell line

As Cellosaurus gives it.

Name
ARPE-19
Accession
CVCL_0145
RRID
RRID:CVCL_0145
Synonyms
ARPE19, Adult Retinal Pigment Epithelial cell line-19, NTC-200, NTC200
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
19Y
Category
Spontaneously immortalized cell line
Derived from
Eye, retina, retinal pigment epithelium (in situ)
Cell type
Retinal pigment epithelial cell
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers69

PaperJournalYearHow we knowRetractedSource
Lipid-Polymeric Nanoencapsulation of Standardized Camellia sinensis Extract Enhances Antiangiogenic Activity and Ocular Biocompatibility.Chem Biodivers2026Its Methods give the RRID and name the linePubMed
Dual impact of EZH1/2-targeted therapy in HTLV-1-associated inflammation: Direct and indirect mechanisms.iScience2026Its Methods give the RRID and name the linePubMed
Olfactory ensheathing cell-derived extracellular vesicles protect the degenerated retinal pigment epithelium by delivering phagocytosis-related proteins.Extracell Vesicles Circ Nucl Acids2026Its Methods give the RRID and name the linePubMed
FOXO6 inhibits SMURF2-mediated ubiquitination and degradation of NR4A1 to promote retinal pigment epithelial cell ferroptosis in diabetic retinopathy.J Cell Commun Signal2026Its Methods give the RRID and name the linePubMed
An Aggregation-Induced Polymerization Poly(Disulfide)-Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS-STING Pathway.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
Deep Proteomic Analysis With Machine Learning Identifies Aqueous Humor Biomarkers of ADAMTSL4-associated Congenital Ectopia Lentis.Invest Ophthalmol Vis Sci2026Its Methods give the RRID and name the linePubMed
Activation of AMPK as a therapeutic strategy for FBXL4-related mitochondrial DNA depletion syndrome.EMBO Mol Med2026Its Methods give the RRID and name the linePubMed
A CRISPR-Cas13d cancer therapeutic enables selective elimination of uveal melanoma.Mol Ther Oncol2026Its Methods give the RRID and name the linePubMed
A sequential dual-drug delivery system for multi-target inhibition of subretinal fibrosis.J Nanobiotechnology2026Its Methods give the RRID and name the linePubMed
EFA6A regulates retinal function through the control of photoreceptor cell activity and structure.iScience2026Its Methods give the RRID and name the linePubMed

1 to 10 of 69

See all 69 papers

Relatives19

RelationCell lineAccessionProblemSource
Derived from itARPE-19 ULK1 KOCVCL_F1YPCell lines
Derived from itARPE-19-LucCVCL_C8URCell lines
Derived from itARPE-19/CNTFCVCL_IQ60Cell lines
Derived from itARPE-19/EGFPCVCL_IQ61Cell lines
Derived from itARPE-19/GDNFCVCL_IQ62Cell lines
Derived from itARPE-19/HPV-16CVCL_6338Cell lines
Derived from itEDITGENE ARPE-19-FLUCCVCL_F5ULCell lines
Derived from itHyCyte ARPE-19 KO-hCYP4V2CVCL_E1J6Cell lines
Derived from itHyCyte ARPE-19 KO-hDDIT4CVCL_E1J7Cell lines
Derived from itHyCyte CT26 mKRAS_p.G12C_c.560G＞T cell lineCVCL_F4KVCell lines

1 to 10 of 19

See all 19 relatives

Cell banks9

Cell bankCatalog numberStatusSource
ATCCCRL-2302ATCC
BCRC60383BCRC
BCRJ0041BCRJ
CCTCCGDC0323Cellosaurus
CLS305025CLS
EDITGENEEDC00338EDITGENE
HysigenTCH-C127Hysigen
IZSLERBS CL 193Cellosaurus
UbigeneYC-C033Ubigene

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0145

GET https://conductscience.org/api/cell-lines/v1/CVCL_0145/papers?page=2

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