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Cell line · CVCL_0186

BxPC-3

Cancer cell line, Homo sapiens. Pancreatic ductal adenocarcinoma. 216 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. BxPC-3. Cell lines, record CVCL_0186. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0186

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Cell line

As Cellosaurus gives it.

Name
BxPC-3
Accession
CVCL_0186
RRID
RRID:CVCL_0186
Synonyms
BxPc-3, BXPC-3, Bx-PC3, BXPC3, BxPC3, BxPc3, Biopsy xenograft of Pancreatic Carcinoma line-3
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
61Y
Category
Cancer cell line
Diseases
Pancreatic ductal adenocarcinoma (NCIt C9120)
Derived from
Pancreas (in situ)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems1

ProblemCellosaurus's note
CautionAdditional TP53 mutation in c.793C>T indicated incorrectly in PubMed=1630814.

Source Cellosaurus

Papers216

PaperJournalYearHow we knowRetractedSource
Pharmacokinetic Tuning Redirects β‐Lapachone From NQO1 Bioactivation to Vimentin‐Targeted Oxidation in CancerAdv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
Engineered αvβ6-targeting peptide‒BSH conjugates for boron neutron capture therapy of pancreatic ductal adenocarcinoma.Acta Pharm Sin B2026Its Methods give the RRID and name the linePubMed
Targeting SERPINB5 and MSLN for Pancreatic Cancer Therapy.Cancers (Basel)2026Its Methods give the RRID and name the linePubMed
Therapeutic Efficacy and Safety of Intraperitoneally Administered 211At-Labeled Gold Nanoparticles for Peritoneally Disseminated Malignancies.Pharmaceutics2026Its Methods give the RRID and name the linePubMed
CPT1A through succinylation regulates the CTCF/LINC01503‒91aa feedback loop to promote gemcitabine resistance in pancreatic ductal adenocarcinoma.Clin Transl Med2026Its Methods give the RRID and name the linePubMed
Targeting PRMT5 Inhibitor-Induced Adaptation in Pancreatic Cancer with the RBM39 Degrader Indisulam.Cancer Res Commun2026Its Methods give the RRID and name the linePubMed
Systematic Targeting of Protein Complexes with Molecular COUPLrs.Cancer Discov2026Its Methods give the RRID and name the linePubMed
Targeting CD24 Activates Macrophages to Reduce Tumor Burden in Preclinical Models of Solid Tumors.Clin Cancer Res2026Its Methods give the RRID and name the linePubMed
Early induction of the Rho-GEF ECT2 drives MEK/ERK oncogenic signaling in pancreatic ductal adenocarcinoma.Oncogene2026Its Methods give the RRID and name the linePubMed
Tobemstomig, a Novel Bispecific Antibody, Preferentially Blocks PD-1 and LAG-3 on CD8 TILs to Expand Stem-like T Cells for Sustained Tumor Control.Cancer Res Commun2026Its Methods give the RRID and name the linePubMed

1 to 10 of 216

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Relatives29

RelationCell lineAccessionProblemSource
Derived from itBXPC-3/Cas9-hygCVCL_C9DPCell lines
Derived from itBx-GEM50CVCL_E4NFCell lines
Derived from itBxPC-3 SMAD2 KOCVCL_E2X4Cell lines
Derived from itBxPC-3 SMAD2/SMAD3 DKOCVCL_E2X5Cell lines
Derived from itBxPC-3 SMAD3 KOCVCL_E2X6Cell lines
Derived from itBxPC-3 XL-1CVCL_E4N8Cell lines
Derived from itBxPC-3 human CCR5CVCL_E8JCCell lines
Derived from itBxPC-3 human CLDN18.2CVCL_XZ31Cell lines
Derived from itBxPC-3 human GPRC5DCVCL_E8JDCell lines
Derived from itBxPC-3 human GPRC5D-HACVCL_E8JBCell lines

1 to 10 of 29

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Cell banks12

Cell bankCatalog numberStatusSource
ATCCCRL-1687ATCC
AddexBioC0018003/27Cellosaurus
BCRC60283BCRC
BCRJ0056BCRJ
CLS305031CLS
DSMZACC-760DSMZ
ECACC93120816ECACC
EDITGENEEDC00328EDITGENE
ICLCHTL96011ICLC
IZSLERBS TCL 4Cellosaurus

1 to 10 of 12

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Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0186

GET https://conductscience.org/api/cell-lines/v1/CVCL_0186/papers?page=2

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