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Cell line · CVCL_0188

C2C12

Spontaneously immortalized cell line, Mus musculus. 145 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. C2C12. Cell lines, record CVCL_0188. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0188

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Cell line

As Cellosaurus gives it.

Name
C2C12
Accession
CVCL_0188
RRID
RRID:CVCL_0188
Synonyms
C2c12, C2-C12, C12
Species
Mus musculus (Mouse)
Sex
Female
Age at sampling
2M
Category
Spontaneously immortalized cell line
Derived from
Skeletal muscle (in situ)
Cell type
Myoblast
Parent
C2 [Mouse myoblast] (CVCL_6812)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers145

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

PaperJournalYearHow we knowRetractedSource
SH3BP2 deficiency in skeletal muscle leads to neuromuscular junction abnormalities and decreased muscle strength.Front Mol Neurosci2026Its Methods give the RRID and name the linePubMed
Alternative splicing of a species- and skeletal muscle-specific microexon diversifies the menu of clathrin heavy chains in mice and rats.iScience2026Its Methods give the RRID and name the linePubMed
Versatile twin layer macromolecular fibers for advanced tissue engineering applications.iScience2026Its Methods give the RRID and name the linePubMed
Prion-Like Protein LENG8-Mediated Nucleation Drives Stress Granule Assembly.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
KDM6A loss enhances oxidative phosphorylation uncovering tissue-level convergent evolution.EMBO J2026Its Methods give the RRID and name the linePubMed
Tumor-Secreted ADAMTSL4 Activates Latent TGFβ1 to Drive Cancer Cachexia.Cancer Discov2026Its Methods give the RRID and name the linePubMed
FOS Regulates Myogenic and Adipogenic Differentiation via Extracellular Matrix Signaling.J Agric Food Chem2026Its Methods give the RRID and name the linePubMed
Transcriptomic Analysis of Pleiotropic Effects of Scandium Chloride on C2C12 Myoblasts.Toxics2026Its Methods give the RRID and name the linePubMed
Myostatin Orchestrates miR-124-Mediated Epigenetic Silencing of ITGB1 to Suppress Skeletal Muscle Growth.Biomolecules2026Its Methods give the RRID and name the linePubMed
Macrophage-Myocyte Cross Talk Induces M1 Polarization and Inflammatory Cytokine Production During Cancer Cachexia.Mediators Inflamm2026Its Methods give the RRID and name the linePubMed

1 to 10 of 145

See all 145 papers

Relatives48

RelationCell lineAccessionProblemSource
ParentC2 [Mouse myoblast]CVCL_6812Cell lines
Derived from itC2C12 Clone 5 DYSF shRNACVCL_AS32Cell lines
Derived from itC2C12 ScrambledCVCL_UR38Cell lines
Derived from itC2C12(Cas9)CVCL_E7J0Cell lines
Derived from itC2C12-BRECVCL_B0JACell lines
Derived from itC2C12-Bmpr1bCVCL_RQ02Cell lines
Derived from itC2C12-EGFPCVCL_C8WRCell lines
Derived from itC2C12-LucCVCL_C8UWCell lines
Derived from itC2C12-R486Q-Bmpr1bCVCL_RQ03Cell lines
Derived from itC2C12-R486W-Bmpr1bCVCL_RQ04Cell lines

Cell banks16

Cell bankCatalog numberStatusSource
ATCCCRL-1772ATCC
Abcamab279976Abcam
AddexBioP0028001/4665Cellosaurus
BCRC60083BCRC
BCRJ0058BCRJ
CCTCCGDC0175Cellosaurus
CLS400476CLS
DSMZACC-565DSMZ
ECACC91031101ECACC
EDITGENEEDC00049EDITGENE

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0188

GET https://conductscience.org/api/cell-lines/v1/CVCL_0188/papers?page=2