Cell line · CVCL_0255

EL4

Cancer cell line, Mus musculus. Mouse precursor T cell lymphoblastic lymphoma/leukemia. 45 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. EL4. Cell lines, record CVCL_0255. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0255

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Cell line

As Cellosaurus gives it.

Name: EL4
Accession: CVCL_0255
RRID: RRID:CVCL_0255
Synonyms: EL-4, EL 4, E.L.4, EL-4 Male
Species: Mus musculus (Mouse)
Sex: Sex unspecified
Age at sampling: Age unspecified
Category: Cancer cell line
Diseases: Mouse precursor T cell lymphoblastic lymphoma/leukemia (NCIt C21925)
Derived from: Ascites (in situ)
Cell type: T-cell
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers45

Paper	Journal	Year	How we know	Source
Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Actin conformation dynamics precede force generation in cytotoxic T lymphocytes.	Commun Biol	2026	Its Methods give the RRID and name the line	PubMed
In Vitro Inhibition of STAT5 Signaling Limits CD8+ T-cell Exhaustion and Improves Outcomes in Adoptive T-cell Therapy.	Cancer Immunol Res	2026	Its Methods give the RRID and name the line	PubMed
Intratumoral Virus-Like Particles Containing a TLR9 Agonist Combined with Systemic αPD-1 Activate Tumor-Specific CD8+ T Cells.	Cancer Res Commun	2026	Its Methods give the RRID and name the line	PubMed
Targeting BCMA in multiple myeloma with a trifunctional NK cell engager.	Cell Rep Med	2026	Its Methods give the RRID and name the line	PubMed
Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD-L1 and T Cell Senescence.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T-cell Antitumor Immunity through Metabolic Reprogramming.	Cancer Immunol Res	2026	Its Methods give the RRID and name the line	PubMed
PD-1 suppresses CAR signaling by forming the inhibitory signalosome colocalizing to CAR microclusters.	Commun Biol	2026	Its Methods give the RRID and name the line	PubMed
Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 45

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Relatives21

Relation	Cell line	Accession	Source
Derived from it	E.G7-OVA	CVCL_3505	Cell lines
Derived from it	EL-4 6.1	CVCL_A0DM	Cell lines
Derived from it	EL-4/cCD20	CVCL_E3E7	Cell lines
Derived from it	EL-4ad	CVCL_8603	Cell lines
Derived from it	EL4-B7-2	CVCL_B6PH	Cell lines
Derived from it	EL4-Luc2 [ATCC]	CVCL_A4BN	Cell lines
Derived from it	EL4-TK	CVCL_F943	Cell lines
Derived from it	EL4-Zbtb1 KO	CVCL_A0PX	Cell lines
Derived from it	EL4-hCD19-LZ	CVCL_E8H0	Cell lines
Derived from it	EL4-hCD20-LZ	CVCL_E6BL	Cell lines

1 to 10 of 21

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Cell banks15

Cell bank	Catalog number	Status	Source
ATCC	TIB-39		ATCC
BCRC	60179		BCRC
CCTCC	GDC0136		Cellosaurus
CLS	300653		CLS
DSMZ	ACC-831		DSMZ
ECACC	85023105		ECACC
Hysigen	TCM-C727		Hysigen
JCRB	IFO50027	Discontinued	Cellosaurus
JCRB	JCRB1350		JCRB
KCB	KCB 2013027YJ		Cellosaurus

1 to 10 of 15

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0255

GET https://conductscience.org/api/cell-lines/v1/CVCL_0255/papers?page=2

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