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Cell line · CVCL_0291

HCT 116

Cancer cell line, Homo sapiens. Colon carcinoma. 711 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. HCT 116. Cell lines, record CVCL_0291. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0291

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Cell line

As Cellosaurus gives it.

Name
HCT 116
Accession
CVCL_0291
RRID
RRID:CVCL_0291
Synonyms
HCT-116, HCT.116, HCT_116, HCT116, HCT116wt, HCT-116/P, HCT-116/parental, CoCL2
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
48Y
Category
Cancer cell line
Diseases
Colon carcinoma (NCIt C4910)
Derived from
Colon (in situ)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers711

5 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

PaperJournalYearHow we knowRetractedSource
PubMed 42999633Immunotargets Ther2026Its Methods give the RRID and name the linePubMed
Two New Metabolites from Moquiniastrum sordidum: Phytochemical Characterization and Multifaceted Bioactivity.ACS Omega2026Its Methods give the RRID and name the linePubMed
Targeting tankyrase scaffolding in the β-catenin destruction complex by PROTAC overcomes the limitation of catalytic inhibitors in colorectal cancer.Elife2026Its Methods give the RRID and name the linePubMed
Inhibition of ferroptosis by microbiota-derived lithocholic acid underlies the intestinal radioprotection of a host defensin-derived oligopeptide.Imeta2026Its Methods give the RRID and name the linePubMed
NDFIP2 Suppresses Colorectal Cancer Metastasis Through DDX3X-Dependent R-Loop Remodeling and GNG13 Transcriptional Activation.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
Previously Undescribed Esters and an Alkaloid From Trollius chinensis With Anti-Inflammatory and Cytotoxic Activities.Chem Biodivers2026Its Methods give the RRID and name the linePubMed
Fatty acid-binding protein 2 suppresses liver metastasis by cytoplasmic sequestration of β-catenin to enhance ferroptosis sensitivity in colon cancer.Cell Death Dis2026Its Methods give the RRID and name the linePubMed
Exploring Chemical Diversity Alongside Antioxidant, Antimicrobial, Antiproliferative, Anti-Inflammatory, and Caenorhabditis elegans Locomotor Responses in Whole, Caps and Stipes of Suillus luteus and Agaricus bisporus.
Pharmaceuticals (Basel)2026Its Methods give the RRID and name the linePubMed
PSY Inhibits Colorectal Cancer Growth and Exhibits an In Vitro Synergistic Interaction with 5-Fluorouracil.Int J Mol Sci2026Its Methods give the RRID and name the linePubMed
FXR and Nrf2 Mediate the Effect of Carbon Ion Irradiation on Drug Transporter OATP1A2 in Cancer Cells.Biology (Basel)2026Its Methods give the RRID and name the linePubMed

1 to 10 of 711

See all 711 papers

Relatives2,101

RelationCell lineAccessionProblemSource
Derived from itAT506.C2CVCL_JY79Cell lines
Derived from itATRFLOXCVCL_2299Cell lines
Derived from itAbcam HCT 116 ABCA1 KOCVCL_D1ZNCell lines
Derived from itAbcam HCT 116 ABCC1 KOCVCL_B8AQCell lines
Derived from itAbcam HCT 116 ABCC4 KOCVCL_D1ZPCell lines
Derived from itAbcam HCT 116 ABL2 KOCVCL_B8ARCell lines
Derived from itAbcam HCT 116 ACACA KOCVCL_D1ZQCell lines
Derived from itAbcam HCT 116 ACKR3 KOCVCL_B8ASCell lines
Derived from itAbcam HCT 116 ACLY KOCVCL_D1ZRCell lines
Derived from itAbcam HCT 116 ACTA2 KOCVCL_B8ATCell lines

1 to 10 of 2,101

See all 2,101 relatives

Cell banks21

Cell bankCatalog numberStatusSource
ABMT8240ABM
ATCCCCL-247ATCC
Abcamab255451Abcam
Abcamab273730Abcam
Abcamab288559Abcam
AddexBioC0009005/41Cellosaurus
BCRC60349BCRC
BCRJ0288BCRJ
CLS300195CLS
DSMZACC-581DSMZ

1 to 10 of 21

See all 21 cell banks

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0291

GET https://conductscience.org/api/cell-lines/v1/CVCL_0291/papers?page=2

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