Cell line · CVCL_0302

HK-2 [Human kidney]

Transformed cell line, Homo sapiens. 87 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. HK-2 [Human kidney]. Cell lines, record CVCL_0302. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0302

On this page

Cell line

As Cellosaurus gives it.

Name: HK-2 [Human kidney]
Accession: CVCL_0302
RRID: RRID:CVCL_0302
Synonyms: Hk-2, HK2, Human Kidney-2
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: Adult
Category: Transformed cell line
Derived from: Kidney, proximal tubule (in situ)
Cell type: Epithelial cell of proximal tubule
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers87

Paper	Journal	Year	How we know	Source
PubMed 42996501	Acta Pharm Sin B	2026	Its Methods give the RRID and name the line	PubMed
Quercetin Attenuates Cisplatin-Induced Nephrotoxicity While Enhancing Antitumor Efficacy in Gastric Cancer via Cell Type-Specific Modulation of the ERK1/2 Pathway.	J Biochem Mol Toxicol	2026	Its Methods give the RRID and name the line	PubMed
TH1177, Clemastine, and Benzhydryl Derivatives Act as Novel Extracellular Blockers of ORAI Channels.	Biomolecules	2026	Its Methods give the RRID and name the line	PubMed
S100A1 Promotes MDM2-Mediated KLF15 Ubiquitination to Regulate ID1-Driven Tubular Injury in Diabetic Kidney Disease.	FASEB J	2026	Its Methods give the RRID and name the line	PubMed
Gut Microbiota-Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1-Mediated Parthanatos.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Naja atra SVPLA2 contributes to venom-induced AKI via HRAS palmitoylation-dependent PI3K-AKT inactivation.	J Lipid Res	2026	Its Methods give the RRID and name the line	PubMed
Hirudin Attenuates Uric Acid-Induced Renal Tubular Injury via TNFRSF6B-Mediated Suppression of NF-κB Signaling.	Pharmacol Res Perspect	2026	Its Methods give the RRID and name the line	PubMed
Diagnostic potential of B-cell translocation gene 2 in IgA nephropathy: Insights from molecular mechanisms.	J Cell Commun Signal	2026	Its Methods give the RRID and name the line	PubMed
CROP2, a Retriever-PROPPIN complex mediating protein export from endosomes to the plasma membrane in human cells.	Elife	2026	Its Methods give the RRID and name the line	PubMed
Tubular tRF‑1:30‑Gln‑CTG‑4 attenuates tubulointerstitial fibrosis by mitigating FBXO7-mediated mitophagy defect in diabetic kidney disease.	Cell Death Dis	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 87

See all 87 papers

Relatives29

Relation	Cell line	Accession	Problem	Source
Derived from it	EDITGENE HK-2-CopGFP	CVCL_F6BV		Cell lines
Derived from it	EDITGENE HK-2[Humankidney]-FLUC	CVCL_F5UP		Cell lines
Derived from it	EDITGENE OCRL (p.Y513C, c.1538A>G) Point Mutation in HK-2 [Human kidney] Cell Line	CVCL_F6D2		Cell lines
Derived from it	HK-2 LPL(p.464K_del)	CVCL_F1YE		Cell lines
Derived from it	HK-2-KIM-1	CVCL_UC05		Cell lines
Derived from it	HK2/Cas9-hyg	CVCL_C9F4		Cell lines
Derived from it	HKC	CVCL_WZ51	Has a recorded problem	Cell lines
Derived from it	HyCyte HK-2 KO-hFOXO3	CVCL_F1QJ		Cell lines
Derived from it	HyCyte HK-2 KO-hIRF8	CVCL_F1QK		Cell lines
Derived from it	HyCyte HK-2 KO-hKDM5A	CVCL_E1LA		Cell lines

1 to 10 of 29

See all 29 relatives

Cell banks9

Cell bank	Catalog number	Source
ATCC	CRL-2190	ATCC
AddexBio	T0011004/4929	Cellosaurus
BCRC	60097	BCRC
CCTCC	GDC0152	Cellosaurus
CLS	305021	CLS
EDITGENE	EDC00272	EDITGENE
KCB	KCB 200815YJ	Cellosaurus
KCLB	22190	KCLB
Ubigene	YC-C140	Ubigene

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0302

GET https://conductscience.org/api/cell-lines/v1/CVCL_0302/papers?page=2

API reference For AI assistants