Cell line · CVCL_0312

HOS

Cancer cell line, Homo sapiens. Osteosarcoma. 55 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. HOS. Cell lines, record CVCL_0312. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0312

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Cell line

As Cellosaurus gives it.

Name: HOS
Accession: CVCL_0312
RRID: RRID:CVCL_0312
Species: Homo sapiens (Human)
Sex: Female
Age at sampling: 13Y
Category: Cancer cell line
Diseases: Osteosarcoma (NCIt C9145); Osteosarcoma (ORDO Orphanet_668)
Derived from: Bone, right femur (in situ)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers55

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
Prognostic characteristics of disulfidptosis-related genes across cancers and their potential implications in osteosarcoma.	Sci Prog	2026	Its Methods give the RRID and name the line	PubMed
ANXA3 activates HIF-1α/VEGF Signaling Via the PI3K/AKT/mTOR Pathway to Promote Osteosarcoma Stem Cell-Like Phenotype.	Stem Cell Rev Rep	2026	Its Methods give the RRID and name the line	PubMed
Ldha Regulates Osteosarcoma Lung Metastasis through Hedgehog Signaling.	Cancer Res Commun	2026	Its Methods give the RRID and name the line	PubMed
Machine Learning-Based Identification and Validation of PYCR1 and PYGM as Prognostic Biomarkers for Osteosarcoma.	Clin Med Insights Oncol	2026	Its Methods give the RRID and name the line	PubMed
Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2-COL3A1 axis.	Mol Oncol	2026	Its Methods give the RRID and name the line	PubMed
LARS promotes osteosarcoma proliferation through leucine-dependent PRIM2 translation and DNA replication activation.	J Exp Clin Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness.	Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
Identification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models.	Mol Cancer Ther	2026	Its Methods give the RRID and name the line	PubMed
Neutrophil elastase promotes low molecular weight cyclin E1 formation to accelerate osteosarcoma proliferation.	Front Immunol	2025	Its Methods give the RRID and name the line	PubMed
Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression.	J Transl Med	2025	Its Methods give the RRID and name the line	PubMed

1 to 10 of 55

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Relatives13

Relation	Cell line	Accession	Source
Derived from it	143B	CVCL_2270	Cell lines
Derived from it	GHOST(3)	CVCL_S489	Cell lines
Derived from it	HOS-B55	CVCL_WK80	Cell lines
Derived from it	HOS-CD4	CVCL_W650	Cell lines
Derived from it	HOS-Luc2-tdT	CVCL_XD62	Cell lines
Derived from it	HOS-mCherry	CVCL_XD63	Cell lines
Derived from it	HOS-pBABE-puro	CVCL_1H17	Cell lines
Derived from it	HOS-tdT	CVCL_XD64	Cell lines
Derived from it	HOS/CMV-Luc#2(c-1)	CVCL_JG33	Cell lines
Derived from it	HOS/GFP	CVCL_A9JG	Cell lines

1 to 10 of 13

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Cell banks14

Cell bank	Catalog number	Status	Source
ATCC	CRL-1543		ATCC
BCRC	60308		BCRC
BCRJ	0339		BCRJ
CCTCC	GDC0251		Cellosaurus
CCTCC	GDC0333		Cellosaurus
CLS	300449		CLS
CLS	300468	Discontinued	Cellosaurus
ECACC	87070202		ECACC
Hysigen	TCH-C261		Hysigen
ICLC	HTL04003		ICLC

1 to 10 of 14

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0312

GET https://conductscience.org/api/cell-lines/v1/CVCL_0312/papers?page=2

API reference For AI assistants