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Cell line · CVCL_0313

HPAF-II

Cancer cell line, Homo sapiens. Pancreatic ductal adenocarcinoma. 83 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. HPAF-II. Cell lines, record CVCL_0313. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0313

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Cell line

As Cellosaurus gives it.

Name
HPAF-II
Accession
CVCL_0313
RRID
RRID:CVCL_0313
Synonyms
HPAF II, HPAFII, HPAF-2, HPAF2, HPAF/CD18, CD18/HPAF, HPAF-II/CD18, CD-18, CD18, CD 18
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
44Y
Category
Cancer cell line
Diseases
Pancreatic ductal adenocarcinoma (NCIt C9120)
Derived from
Ascites (metastatic)
Parent
HPAF (CVCL_B284)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems2

ProblemCellosaurus's note
CautionCould not find proof that the CD18 subline of HPAF is really HPAF-II but many indirect evidences points in this direction. If someone read this comment and can help us, please do.
CautionTP53 mutation indicated incorrectly as being at c.452C>T in PubMed=1764370.

Papers83

3 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

PaperJournalYearHow we knowRetractedSource
Activation of PP2A-B56a leads to aberrant EGFR signaling and proliferative phenotypes in PDAC.Mol Cancer Ther2026Its Methods give the RRID and name the linePubMed
Allele-Specific Mechanisms Guide Salvage Therapy to Overcome Daraxonrasib Resistance in Pancreatic Cancer.Cancer Res2026Its Methods give the RRID and name the linePubMed
A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer.Cancer Cell2026Its Methods give the RRID and name the linePubMed
A Stress-Adaptive Lipid Kinase Axis Defines Metabolic Vulnerabilities in Neuroendocrine Prostate Cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed
Overcoming Daraxonrasib Resistance: Allele-Specific Mechanisms Guide Salvage Therapy in Pancreatic Cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed
Early induction of the Rho-GEF ECT2 drives MEK/ERK oncogenic signaling in pancreatic ductal adenocarcinoma.Oncogene2026Its Methods give the RRID and name the linePubMed
Characterization and therapeutic suppression of KEAP1-NRF2-driven resistance to KRAS inhibitors in pancreatic and lung cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed
An Integrin β6-Targeted Antibody-Drug Conjugate Optimized for Intravesical Delivery to Treat Non-Muscle-Invasive Bladder Cancer.Mol Cancer Ther2026Its Methods give the RRID and name the linePubMed
ADCE-T02: A Next-generation Antibody-Drug Conjugate Targeting Tissue Factor Demonstrates Superior Preclinical Efficacy and Tolerability.Mol Cancer Ther2026Its Methods give the RRID and name the linePubMed
A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy.Cell2026Its Methods give the RRID and name the linePubMed

1 to 10 of 83

See all 83 papers

Relatives1

RelationCell lineAccessionProblem
ParentHPAFCVCL_B284

Source Cell lines

Cell banks3

Cell bankCatalog numberStatusSource
ATCCCRL-1997ATCC
CLS305088CLS
IZSLERBS TCL 170Cellosaurus

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0313

GET https://conductscience.org/api/cell-lines/v1/CVCL_0313/papers?page=2