Cell line · CVCL_0317

HT-1080

Cancer cell line, Homo sapiens. Fibrosarcoma. 111 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. HT-1080. Cell lines, record CVCL_0317. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0317

On this page

Cell line

As Cellosaurus gives it.

Name: HT-1080
Accession: CVCL_0317
RRID: RRID:CVCL_0317
Synonyms: Ht-1080, HT 1080, HT1080, HT 1080.T
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 35Y
Category: Cancer cell line
Diseases: Fibrosarcoma (NCIt C3043); Fibrosarcoma (ORDO Orphanet_2030)
Derived from: Bone, pelvis, acetabulum (in situ)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems1

Problem	Cellosaurus's note
Caution	This cell line is considered by some researchers to represent a dedifferentiated chondrosarcoma due to the presence of an IDH1 mutation (PubMed=26368816).

Source Cellosaurus

Papers111

2 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

Paper	Journal	Year	How we know	Source
Targeting GPX4 and FSP1 to exploit ferroptotic vulnerability in Ewing sarcoma.	Front Oncol	2026	Its Methods give the RRID and name the line	PubMed
A guide to selecting high-performing antibodies for Netrin-1 (UniProt ID: O95631) for use in western blot and immunoprecipitation.	F1000Res	2026	Its Methods give the RRID and name the line	PubMed
An ancient alpharetrovirus lineage in bats: Evolutionary insights and possible roles in reproduction.	PLoS Genet	2026	Its Methods give the RRID and name the line	PubMed
Model-dependent GD2 upregulation in Ewing sarcoma with the EZH2 inhibitor tazemetostat: Prerequisites for combination with GD2-specific CAR T cells.	Res Sq	2026	Its Methods give the RRID and name the line	PubMed
Systematic Targeting of Protein Complexes with Molecular COUPLrs.	Cancer Discov	2026	Its Methods give the RRID and name the line	PubMed
Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple-Negative Breast Cancer.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
p300 Degradation by the p53-SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
MORC3 represses a tandem repeat enhancer to regulate interferon.	EMBO J	2026	Its Methods give the RRID and name the line	PubMed
MiR-940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Drug Screening of Sarcoma Cells: Finding Shared Sensitivities.	Cancer Res Commun	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 111

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Relatives62

Relation	Cell line	Accession	Source
Derived from it	2C4 [Human fibrosarcoma]	CVCL_1D50	Cell lines
Derived from it	2fTGH	CVCL_0115	Cell lines
Derived from it	EDITGENE HT-1080-CopGFP	CVCL_F6A3	Cell lines
Derived from it	EDITGENE HT-1080-FLUC	CVCL_F5SL	Cell lines
Derived from it	EDITGENE ht1080-Cas9	CVCL_F5PY	Cell lines
Derived from it	FLYA13	CVCL_8870	Cell lines
Derived from it	FLYRD18	CVCL_8871	Cell lines
Derived from it	HL116	CVCL_RW47	Cell lines
Derived from it	HP	CVCL_3715	Cell lines
Derived from it	HT-1080 JH-1/FIX	CVCL_XG90	Cell lines

1 to 10 of 62

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Cell banks20

Cell bank	Catalog number	Status	Source
ABM	T8971		ABM
ATCC	CCL-121		ATCC
ATCC	CRL-7951	Discontinued	Cellosaurus
BCRC	60037		BCRC
BCRJ	0110		BCRJ
CCTCC	GDC0105		Cellosaurus
CLS	300216		CLS
DSMZ	ACC-315		DSMZ
ECACC	85111505		ECACC
EDITGENE	EDC00188		EDITGENE

1 to 10 of 20

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0317

GET https://conductscience.org/api/cell-lines/v1/CVCL_0317/papers?page=2

API reference For AI assistants