Cell line · CVCL_0327

Hepa 1-6

Cancer cell line, Mus musculus. Hepatocellular carcinoma of the mouse. 79 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. Hepa 1-6. Cell lines, record CVCL_0327. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0327

On this page

Cell line

As Cellosaurus gives it.

Name: Hepa 1-6
Accession: CVCL_0327
RRID: RRID:CVCL_0327
Synonyms: HEPA 1-6, Hepa-1-6, Hepa1-6
Species: Mus musculus (Mouse)
Sex: Female
Age at sampling: Age unspecified
Category: Cancer cell line
Diseases: Hepatocellular carcinoma of the mouse (NCIt C38756)
Derived from: Liver (in situ)
Parent: Hepa-1 (CVCL_S550)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers79

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
PubMed 43000531	Nat Commun	2026	Its Methods give the RRID and name the line	PubMed
Chronic stress activates a hypothalamic vagal circuit to promote hepatocellular carcinoma progression in male mice.	Nat Commun	2026	Its Methods give the RRID and name the line	PubMed
Liver-specific amino acid metabolism impacts on efficacy of cancer immunotherapy.	Oncogene	2026	Its Methods give the RRID and name the line	PubMed
Fedratinib treatment correlates with suppressed STAT3/AKT/calpain-1 signaling and inhibits hepatocellular carcinoma progression.	Transl Gastroenterol Hepatol	2026	Its Methods give the RRID and name the line	PubMed
XIAP inhibition augments personalized neoantigen vaccine-driven antitumor immunity in orthotopic hepatocellular carcinoma.	J Immunother Cancer	2026	Its Methods give the RRID and name the line	PubMed
Metabolic Reprogramming of NSUN2-Mediated m5C Modification Promotes the Progression of Hepatocellular Carcinoma by Restricting Natural Killer Cell-Mediated Cytotoxicity.	Cancer Commun (Lond)	2026	Its Methods give the RRID and name the line	PubMed
Targeting circulating fatty acid-binding protein 4 ameliorates obesity-associated hepatic steatosis.	JHEP Rep	2026	Its Methods give the RRID and name the line	PubMed
Mechanosensors Collaborate to Regulate DNA Damage Repair in Hepatocellular Carcinoma.	Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
Targeting p21-High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Bile acid retention in efferocytic macrophages shapes their inflammatory status during cholangitis.	J Exp Med	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 79

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Relatives35

Relation	Cell line	Accession	Source
Parent	Hepa-1	CVCL_S550	Cell lines
Derived from it	Dt81Hepa1-6	CVCL_IU28	Cell lines
Derived from it	EDITGENE Hepa1-6-Cas9	CVCL_F5QV	Cell lines
Derived from it	EDITGENE Hepa1-6-CopGFP	CVCL_F6C5	Cell lines
Derived from it	EDITGENE Hepa1-6-FLUC	CVCL_F5UN	Cell lines
Derived from it	Hepa 1-6-Luc	CVCL_C8Y7	Cell lines
Derived from it	Hepa 1-6/10R	CVCL_A5BH	Cell lines
Derived from it	Hepa/8F5	CVCL_RI52	Cell lines
Derived from it	Hepa1-6-Fluc-Neo	CVCL_RA19	Cell lines
Derived from it	Hepa1-6-Fluc-Neo/eGFP-Puro	CVCL_RA20	Cell lines

1 to 10 of 35

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Cell banks13

Cell bank	Catalog number	Source
ATCC	CRL-1830	ATCC
AddexBio	C0015005/4999	Cellosaurus
BCRC	60051	BCRC
CCTCC	GDC0313	Cellosaurus
CLS	400474	CLS
DSMZ	ACC-175	DSMZ
ECACC	92110305	ECACC
EDITGENE	EDC00250	EDITGENE
Hysigen	TCM-C734	Hysigen
IZSLER	BS TCL 157	Cellosaurus

1 to 10 of 13

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0327

GET https://conductscience.org/api/cell-lines/v1/CVCL_0327/papers?page=2

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