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Cell line · CVCL_0417

MDA-MB-435

Cancer cell line, Homo sapiens. Amelanotic melanoma. Cellosaurus records it as contaminated. 45 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. MDA-MB-435. Cell lines, record CVCL_0417. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0417

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Cell line

As Cellosaurus gives it.

Name
MDA-MB-435
Accession
CVCL_0417
RRID
RRID:CVCL_0417
Synonyms
MDA-MB435, MDAMB435, MDA.MB.435, MDA-435, MDA 435, MDA435, MD Anderson-Metastatic Breast-435
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
33Y
Category
Cancer cell line
Diseases
Amelanotic melanoma (NCIt C3802)
Derived from
Right buttock, hypodermis (metastatic)
Parent
M14 (CVCL_1395)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems1

ProblemCellosaurus's note
Contaminated
Shown to be a M14 derivative (PubMed=17004106; PubMed=18304946; PubMed=20143388; PubMed=28940260). Originally thought to originate from the pleural effusion of a breast carcinoma from a 31 year old patient. See also PubMed=19549886 for a dissenting but incorrect view that states that M14 is a breast cancer cell line.

Source Cellosaurus

Papers45

PaperJournalYearHow we knowRetractedSource
Design optimization of antibody-ligand motifs to enhance CAR-T redirection activity against solid tumors.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
HTS384 NCI60: The Next Phase of the NCI60 Screen.Cancer Res2024Cellosaurus cites it, and its Methods give the RRID and name the linePubMed
Susceptibility of Melanoma Cells to Targeted Therapy Correlates with Protection by Blood Neutrophils.Cancers (Basel)2024Its Methods give the RRID and name the linePubMed
eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer.Sci Signal2024Its Methods give the RRID and name the linePubMed
Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors.Cell Rep Med2021Its Methods give the RRID and name the linePubMed
YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models.Cell Oncol (Dordr)2021Its Methods give the RRID and name the linePubMed
89Zr-Labeled Domain II-Specific scFv-Fc ImmunoPET Probe for Imaging Epidermal Growth Factor Receptor In Vivo.Cancers (Basel)2021Its Methods give the RRID and name the linePubMed
Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines.iScience2019Cellosaurus cites itPubMed
Authentication of M14 melanoma cell line proves misidentification of MDA-MB-435 breast cancer cell line.Int J Cancer2018Cellosaurus cites itPubMed
Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.Breast Cancer Res Treat2018Cellosaurus cites itPubMed

1 to 10 of 45

See all 45 papers

Relatives13

RelationCell lineAccessionProblemSource
ParentM14CVCL_1395Cell lines
Derived from it435.eBCVCL_0124Has a recorded problemCell lines
Derived from it435.neoCVCL_F0XMHas a recorded problemCell lines
Derived from itM4A4CVCL_B057Has a recorded problemCell lines
Derived from itMDA 435TRCVCL_J435Has a recorded problemCell lines
Derived from itMDA-MB-435-BAGCVCL_R957Has a recorded problemCell lines
Derived from itMDA-MB-435-LCC15CVCL_B055Has a recorded problemCell lines
Derived from itMDA-MB-435-Luc#1CVCL_4Y10Has a recorded problemCell lines
Derived from itMDA-MB-435ECVCL_F0XNHas a recorded problemCell lines
Derived from itMDA-MB-435SCVCL_0622Has a recorded problemCell lines

1 to 10 of 13

See all 13 relatives

Cell banks1

Cell bankCatalog numberStatus
NCI-DCTDMDA-MB-435

Source Cellosaurus

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

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The record and each of its lists are JSON, twenty rows a page. No key.

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