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Cell line · CVCL_0418

MDA-MB-453

Cancer cell line, Homo sapiens. Breast adenocarcinoma. 114 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. MDA-MB-453. Cell lines, record CVCL_0418. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0418

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Cell line

As Cellosaurus gives it.

Name
MDA-MB-453
Accession
CVCL_0418
RRID
RRID:CVCL_0418
Synonyms
MDA-MB 453, MDA MB 453, MDA-MB453, MDAMB453, MDA-453, MDA453, MD Anderson-Metastatic Breast-453
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
48Y
Category
Cancer cell line
Diseases
Breast adenocarcinoma (NCIt C5214)
Derived from
Pericardial effusion (metastatic)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers114

2 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

PaperJournalYearHow we knowRetractedSource
ZBTB1 Regulates Glycolysis and Chemotherapy Resistance Through Interacting with c-Myc in Triple Negative Breast Cancer.Cancers (Basel)2026Its Methods give the RRID and name the linePubMed
Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
Distinct metabolic dependency on BCAA defines cancer stemness and malignancy in human triple-negative breast cancer.Cell Rep2026Its Methods give the RRID and name the linePubMed
UBE2L6 promotes invasion and metastasis of triple-negative breast cancer by enhancing autophagy through STK38 ISGylation.Cell Mol Life Sci2026Its Methods give the RRID and name the linePubMed
Molecular Design and Preclinical Evaluation of GenSci143, a Novel B7-H3-Directed and PSMA-Directed Bispecific Antibody-Drug Conjugate, for the Treatment of Prostate Cancer.Mol Cancer Ther2026Its Methods give the RRID and name the linePubMed
Metastasis-Associated Wound Repair Promotes Reciprocal Lung Epithelium Activation and Breast Cancer Metastatic Outgrowth.Cancer Res Commun2026Its Methods give the RRID and name the linePubMed
AXL-SHC1 signaling axis mediates adaptive resistance to HER2-targeted tyrosine kinase inhibitors in HER2-aberrant lung and gastric cancers.NPJ Precis Oncol2026Its Methods give the RRID and name the linePubMed
HER2 Heterogeneous Breast Cancer Models Reveal Novel Therapeutic Targets and Subclonal Dynamics during Evolution to Resistance to HER2-Targeted Therapies.Cancer Discov2026Its Methods give the RRID and name the linePubMed
A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy.Cell2026Its Methods give the RRID and name the linePubMed
Discovery of novel circular RNAs of the apoptosis-related BAX gene in breast cancer, by combining nanopore and next-generation sequencing.Mol Genet Genomics2026Its Methods give the RRID and name the linePubMed

1 to 10 of 114

See all 114 papers

Relatives4

RelationCell lineAccessionProblemSource
Derived from itHyCyte MDA-MB-453 KO-hCPB1CVCL_F4GLCell lines
Derived from itHyCyte MDA-MB-453 stable cell line for hCPB1 overexpressionCVCL_F4UACell lines
Derived from itMDA-MB-453 Ad15CVCL_ZZ23Cell lines
Derived from itMDA-kb2CVCL_6421Cell lines

Cell banks9

Cell bankCatalog numberStatusSource
ATCCHTB-131ATCC
BCRC60429BCRC
CLS305042DiscontinuedCellosaurus
DSMZACC-65DSMZ
ICLCHTL01013ICLC
IZSLERBS TCL 247Cellosaurus
KCLB30131KCLB
NCBI_IranC214Cellosaurus
RCBRCB1192RCB

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0418

GET https://conductscience.org/api/cell-lines/v1/CVCL_0418/papers?page=2