Cell line · CVCL_0422

MDCK

Spontaneously immortalized cell line, Canis lupus familiaris. 79 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. MDCK. Cell lines, record CVCL_0422. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0422

On this page

Cell line

As Cellosaurus gives it.

Name: MDCK
Accession: CVCL_0422
RRID: RRID:CVCL_0422
Synonyms: MDCK (NBL-2), MDCK(NBL-2), NBL-2, Madin-Darby Canine Kidney, Madin Darby Canine Kidney
Species: Canis lupus familiaris (Dog)
Sex: Female
Age at sampling: Adult
Category: Spontaneously immortalized cell line
Derived from: Kidney (in situ)
Cell type: Epithelial cell of kidney
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems1

Problem	Cellosaurus's note
Caution	There seem to be two distinct cell lines which were assigned NCBI_Iran catalog number C426.

Source Cellosaurus

Papers79

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
Preclinical Safety and Immunogenicity Characterization of Emulsivant 70: A Promising Candidate Adjuvant for Emulsified Veterinary Vaccines	J Immunol Res	2026	Its Methods give the RRID and name the line	PubMed
Monitoring kinetic changes and restriction of influenza A virus RNA species during infection using a Flu-Stranded CRISPR platform.	mBio	2026	Its Methods give the RRID and name the line	PubMed
Consensus H3N2 HA immunogens incorporating key antigenic mutations elicit broad-spectrum neutralizing responses.	Emerg Microbes Infect	2026	Its Methods give the RRID and name the line	PubMed
Host cell entry and neutralisation sensitivity of H3N2 influenza A virus subclade K.	NPJ Vaccines	2026	Its Methods give the RRID and name the line	PubMed
Assessment of Humoral Immunogenicity of ChAdOx1 H5 HA Influenza Vaccine for Dairy Cattle.	Vaccines (Basel)	2026	Its Methods give the RRID and name the line	PubMed
Characterisation of a human monoclonal antibody targeting a conserved epitope at the base of the HA head of influenza A(H3N2) virus.	EBioMedicine	2026	Its Methods give the RRID and name the line	PubMed
HMGA2 regulates fear and growth: Canine GWAS and functional evidence.	iScience	2026	Its Methods give the RRID and name the line	PubMed
Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity.	FEBS Lett	2026	Its Methods give the RRID and name the line	PubMed
Streamlined Synthesis and Structure-Activity Relationship Analysis of 2-Amidothiophene-3-Carboxamides Targeting Influenza Polymerase PA-PB1 Heterodimerization.	ChemMedChem	2026	Its Methods give the RRID and name the line	PubMed
Nasal RNA-scaffold-protein vaccine protects mice from human H5N1 clade 2.3.4.4b virus lethal infection and safeguards against vaccine-unmatched viruses.	EBioMedicine	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 79

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Relatives85

Relation	Cell line	Accession	Source
Derived from it	DoCl1 (S+L-)	CVCL_4164	Cell lines
Derived from it	EDITGENE MDCK(NBL-2)-CopGFP	CVCL_F6CQ	Cell lines
Derived from it	EDITGENE MDCK(NBL-2)-FLUC	CVCL_F5V8	Cell lines
Derived from it	HyCyte MDCK stable cell line for hFCGRT&hB2M overexpression	CVCL_F4UL	Cell lines
Derived from it	LINTERNA MDCK	CVCL_YJ87	Cell lines
Derived from it	Luc9.1	CVCL_GY95	Cell lines
Derived from it	MDCK 33016	CVCL_2A36	Cell lines
Derived from it	MDCK 9B9-1B1	CVCL_DF69	Cell lines
Derived from it	MDCK 9B9-1E4	CVCL_DF70	Cell lines
Derived from it	MDCK Actin-cpstFRET-Actin	CVCL_ZV91	Cell lines

1 to 10 of 85

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Cell banks23

Cell bank	Catalog number	Status	Source
ABM	T8979		ABM
ATCC	CCL-34		ATCC
ATCC	CRL-6253	Discontinued	Cellosaurus
AddexBio	P0014003/4928		Cellosaurus
BCRC	60004		BCRC
BCRJ	0168		BCRJ
BEI_Resources	NR-2628		BEI_Resources
CCLV	CCLV-RIE 0083		Cellosaurus
CCTCC	GDC0012		Cellosaurus
CCTCC	GDC0401		Cellosaurus

1 to 10 of 23

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0422

GET https://conductscience.org/api/cell-lines/v1/CVCL_0422/papers?page=2

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