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Cell line · CVCL_0445

MeWo

Cancer cell line, Homo sapiens. Cutaneous melanoma. 64 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. MeWo. Cell lines, record CVCL_0445. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0445

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Cell line

As Cellosaurus gives it.

Name
MeWo
Accession
CVCL_0445
RRID
RRID:CVCL_0445
Synonyms
MEWO, Mewo, Me Wo, Me-Wo, Mevo, SK-MEL-MeWo, Mel-MeWo, BI-Mel, EST50
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
78Y
Category
Cancer cell line
Diseases
Cutaneous melanoma (NCIt C3510)
Derived from
Lymph node (metastatic)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers64

PaperJournalYearHow we knowRetractedSource
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells.FEBS Open Bio2026Its Methods give the RRID and name the linePubMed
Out-of-frame CBX3::ALK fusion drives ALK activation and therapy response.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
Thrombomodulin facilitates melanoma progression via FAK- and ezrin-mediated phenotypic plasticity.J Biomed Sci2026Its Methods give the RRID and name the linePubMed
Tissue-dependent mechanosensing by cells derived from human tumors.NPJ Biol Phys Mech2025Its Methods give the RRID and name the linePubMed
Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells.Cancer Res2025Its Methods give the RRID and name the linePubMed
NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1-Mutant Melanoma.Cancer Res2025Its Methods give the RRID and name the linePubMed
Single-Cell Transcriptomic Landscape Deciphers Intratumoral Heterogeneity and Subtypes of Acral and Mucosal Melanomas.Clin Cancer Res2025Its Methods give the RRID and name the linePubMed
RAC1-Amplified and RAC1-A159V Hotspot-Mutated Head and Neck Cancer Sensitive to the Rac Inhibitor EHop-016 In Vivo: A Proof-of-Concept Study.Cancers (Basel)2025Its Methods give the RRID and name the linePubMed
SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism.Int J Cancer2025Its Methods give the RRID and name the linePubMed
PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients.Mol Oncol2024Its Methods give the RRID and name the linePubMed

1 to 10 of 64

See all 64 papers

Relatives11

RelationCell lineAccessionProblemSource
Derived from itMeWo CIS 0.01CVCL_AZ60Cell lines
Derived from itMeWo CIS 1CVCL_AZ74Cell lines
Derived from itMeWo ETO 0.1CVCL_AZ61Cell lines
Derived from itMeWo ETO 1CVCL_AZ62Cell lines
Derived from itMeWo FOTE 4CVCL_AZ75Cell lines
Derived from itMeWo FOTE 40CVCL_AZ76Cell lines
Derived from itMeWo LNI 6ICVCL_Y663Cell lines
Derived from itMeWo VIN 0.5CVCL_AZ63Cell lines
Derived from itMeWo VIN 5CVCL_AZ77Cell lines
Derived from itMeWo-LC1CVCL_U937Cell lines

Cell banks7

Cell bankCatalog numberStatusSource
ATCCHTB-65ATCC
BCRC60540BCRC
BCRJ0358BCRJ
CLS300285CLS
ECACC93082609ECACC
ICLCHTL97019ICLC
JCRBJCRB0066JCRB

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0445

GET https://conductscience.org/api/cell-lines/v1/CVCL_0445/papers?page=2