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Cell line · CVCL_0458

NCI-H295R

Cancer cell line, Homo sapiens. Adrenal cortex carcinoma. 35 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. NCI-H295R. Cell lines, record CVCL_0458. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0458

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Cell line

As Cellosaurus gives it.

Name
NCI-H295R
Accession
CVCL_0458
RRID
RRID:CVCL_0458
Synonyms
NCI H295R, NCIH295R, H295R, H-295R, H295R-S1
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
48Y
Category
Cancer cell line
Diseases
Adrenal cortex carcinoma (NCIt C9325); Adrenocortical carcinoma (ORDO Orphanet_1501)
Derived from
Adrenal gland (in situ)
Parent
NCI-H295 (CVCL_0456)
Entry created
2012-04-04
Entry updated
2025-11-27

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers35

PaperJournalYearHow we knowRetractedSource
IGF2R: a new player in the IGF2 loop sustaining adrenocortical carcinogenesis.Cell Commun Signal2026Its Methods give the RRID and name the linePubMed
The essential role of the redox balance in adrenal steroidogenesis.Arch Endocrinol Metab2026Its Methods give the RRID and name the linePubMed
Roflumilast Enhances Liraglutide's Atrial Natriuretic Peptide-Dependent Suppression of Adrenal Aldosterone Secretion.Int J Mol Sci2026Its Methods give the RRID and name the linePubMed
Unfolded Protein Response as a Therapeutic Target: 4-(Heptyloxy)phenol Induces Programmed Cell Death in Ewing Sarcoma.Mol Cancer Ther2026Its Methods give the RRID and name the linePubMed
β-catenin functions as a molecular adapter for disordered cBAF interactions.Mol Cell2025Its Methods give the RRID and name the linePubMed
Defactinib in Combination with Mitotane Can Be an Effective Treatment in Human Adrenocortical Carcinoma.Int J Mol Sci2025Its Methods give the RRID and name the linePubMed
Emerging role of IGF1R and IR expression and localisation in adrenocortical carcinomas.Cell Commun Signal2025Its Methods give the RRID and name the linePubMed
Identification of CENPM as a key gene driving adrenocortical carcinoma metastasis via physical interaction with immune checkpoint ligand FGL1.Clin Transl Med2025Its Methods give the RRID and name the linePubMed
Therapeutic potential of targeting the FLNA-regulated Wee1 kinase in adrenocortical carcinomas.Int J Cancer2025Its Methods give the RRID and name the linePubMed
Development and Characterization of 3-Dimensional Cell Culture Models of Adrenocortical Carcinoma.Endocrinology2024Its Methods give the RRID and name the linePubMed

1 to 10 of 35

See all 35 papers

Relatives5

RelationCell lineAccessionProblemSource
ParentNCI-H295CVCL_0456Cell lines
Derived from itHAC13CVCL_5V09Cell lines
Derived from itHAC15CVCL_S898Has a recorded problemCell lines
Derived from itHAC50CVCL_5V08Cell lines
Derived from itHyCyte NCI-H295R KO-hNPC1CVCL_F1SACell lines

Cell banks3

Cell bankCatalog numberStatusSource
ATCCCRL-2128ATCC
CLS300483CLS
KCBKCB 2015009YJCellosaurus

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0458

GET https://conductscience.org/api/cell-lines/v1/CVCL_0458/papers?page=2