Cell line · CVCL_0459

NCI-H460

Cancer cell line, Homo sapiens. Lung large cell carcinoma. 196 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. NCI-H460. Cell lines, record CVCL_0459. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0459

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Cell line

As Cellosaurus gives it.

Name: NCI-H460
Accession: CVCL_0459
RRID: RRID:CVCL_0459
Synonyms: NCI.H460, H460, H-460, NCIH460, NCI-HUT-460, NCI-460
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: Age unspecified
Category: Cancer cell line
Diseases: Lung large cell carcinoma (NCIt C4450)
Derived from: Pleural effusion (metastatic)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers196

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
Waterpipe Smoke Condensate Impairs p53 Nuclear Localization in Association with HIF-1α Stabilization.	Int J Mol Sci	2026	Its Methods give the RRID and name the line	PubMed
A Multi-Targeting Chimeric Antigen Receptor-T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non-Small Cell Lung Cancer.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway.	Int J Oncol	2026	Its Methods give the RRID and name the line	PubMed
SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA-PKcs/CHK1 replicative checkpoint to inhibit cell growth in non-small cell lung cancer.	Mol Oncol	2026	Its Methods give the RRID and name the line	PubMed
CXCR4+ circulating tumor cells (CTCs) accumulate in subcutaneous, immune suppressive, CXCL12-loaded-hydrogel.	Mater Today Bio	2026	Its Methods give the RRID and name the line	PubMed
KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion.	Apoptosis	2026	Its Methods give the RRID and name the line	PubMed
PFKFB4 Deubiquitination by USP10 Enhances Fumarate Metabolism to Orchestrate the KDM1A/Rad51 Axis and Confer Radioresistance in Lung Cancer.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Engineering iron oxide nanoparticles for enhanced radiosensitization.	RSC Adv	2026	Its Methods give the RRID and name the line	PubMed
Inhibition of cyclin-dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation.	Mol Oncol	2026	Its Methods give the RRID and name the line	PubMed
Cannabigerol and Cannabichromene Induce Lung Cancer Cell Death and Apoptosis-Contribution of PPARα to Cannabigerol Effects.	Antioxidants (Basel)	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 196

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Relatives23

Relation	Cell line	Accession	Problem	Source
Derived from it	EDITGENE NCI-H460-Cas9	CVCL_F5QC		Cell lines
Derived from it	EDITGENE NCI-H460-CopGFP	CVCL_F6B3		Cell lines
Derived from it	EDITGENE NCI-H460-FLUC	CVCL_F5TF		Cell lines
Derived from it	H460/CIS	CVCL_A9CH		Cell lines
Derived from it	H460/CisR	CVCL_C5S1		Cell lines
Derived from it	H460/TR	CVCL_C5ST		Cell lines
Derived from it	H460R	CVCL_UW76		Cell lines
Derived from it	HROBML03	CVCL_1D09	Has a recorded problem	Cell lines
Derived from it	HyCyte NCI-H460 KO-hIMPDH2	CVCL_F1SB		Cell lines
Derived from it	HyCyte NCI-H460 KO-hTRIM28	CVCL_F4GF		Cell lines

1 to 10 of 23

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Cell banks14

Cell bank	Catalog number	Source
ATCC	HTB-177	ATCC
AddexBio	C0016003/39	Cellosaurus
BCRC	60373	BCRC
BCRJ	0416	BCRJ
CCLV	CCLV-RIE 0962	Cellosaurus
CCTCC	GDC0109	Cellosaurus
CLS	305020	CLS
DSMZ	ACC-737	DSMZ
EDITGENE	EDC00286	EDITGENE
Hysigen	TCH-C286	Hysigen

1 to 10 of 14

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0459

GET https://conductscience.org/api/cell-lines/v1/CVCL_0459/papers?page=2

API reference For AI assistants