Cell line · CVCL_0481

PC12

Cancer cell line, Rattus norvegicus. Rat adrenal gland pheochromocytoma. 85 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. PC12. Cell lines, record CVCL_0481. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0481

On this page

Cell line

As Cellosaurus gives it.

Name: PC12
Accession: CVCL_0481
RRID: RRID:CVCL_0481
Synonyms: PC-12, PC 12, PC12.1
Species: Rattus norvegicus (Rat)
Sex: Male
Age at sampling: Age unspecified
Category: Cancer cell line
Diseases: Rat adrenal gland pheochromocytoma (NCIt C121568)
Derived from: Adrenal gland (in situ)
Entry created: 2012-04-04
Entry updated: 2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers85

Paper	Journal	Year	How we know	Source
A Dual-Functional Nanoplatform Targeting the dsDNA-cGAS Axis to Mitigate Disc Degeneration and Aberrant Innervation.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Laminin-triggered integrin signaling potentiates γ-enolase-induced neurite outgrowth.	Mol Cell Biochem	2026	Its Methods give the RRID and name the line	PubMed
Study on the Antidepressant Effect and Mechanism of Water Extract of Semiliquidambar cathayensis (WESC) Based on the GSK3β/NF-κB Signaling Pathway.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Acupuncture alleviates secondary brain injury in intracerebral hemorrhage-induced rats through activating the LKLF/Mfn2 pathway.	Braz J Med Biol Res	2026	Its Methods give the RRID and name the line	PubMed
Chromogranin A mediates glucocorticoid-induced enhancement of vesicular dopamine storage and secretion in PC12 cells.	J Biol Chem	2026	Its Methods give the RRID and name the line	PubMed
Exercise-derived exosomal miR-151-3p: An innovative anti-inflammatory and antioxidant therapeutic for spinal cord injury.	Bioact Mater	2026	Its Methods give the RRID and name the line	PubMed
Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Harpagide attenuates cerebral ischemic injury by modulating mitochondrial calcium homeostasis associated with the AMPK-MCU axis.	Sci Rep	2026	Its Methods give the RRID and name the line	PubMed
"Membrane-Guided" Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
H2S induces apoptosis of tumors with high IDO1 expression via NR4A1-BCL-2 and SOCS3 pathways.	Cell Mol Biol Lett	2026	Its Methods give the RRID and name the line	PubMed

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Relatives62

Relation	Cell line	Accession	Source
Derived from it	123.7	CVCL_0109	Cell lines
Derived from it	A126-1B2	CVCL_0133	Cell lines
Derived from it	A208-4	CVCL_X983	Cell lines
Derived from it	A208-7	CVCL_X984	Cell lines
Derived from it	AB.11	CVCL_X985	Cell lines
Derived from it	HyCyte CT26 mKRAS_p.G12C_c.573G＞T cell line	CVCL_F4L1	Cell lines
Derived from it	HyCyte PC12 KO-rYthdc2	CVCL_F1ST	Cell lines
Derived from it	HyCyte PC12 rFgfr1_p.N546K_c.1638C>TG cell line	CVCL_F4K7	Cell lines
Derived from it	HyCyte PC12 stable cell line for rNlgn1 overexpression	CVCL_F4U8	Cell lines
Derived from it	LINTERNA PC-12	CVCL_YJ89	Cell lines

1 to 10 of 62

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Cell banks20

Cell bank	Catalog number	Source
ATCC	CRL-1721	ATCC
Abcam	ab279978	Abcam
AddexBio	C0032001/4927	Cellosaurus
BCRC	60048	BCRC
BCRJ	0203	BCRJ
CCTCC	GDC0006	Cellosaurus
CLS	500311	CLS
DSMZ	ACC-159	DSMZ
ECACC	88022401	ECACC
ICLC	ATL98004	ICLC

1 to 10 of 20

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0481

GET https://conductscience.org/api/cell-lines/v1/CVCL_0481/papers?page=2

API reference For AI assistants