Cell line · CVCL_0525
SK-HEP-1
Cancer cell line, Homo sapiens. Liver and intrahepatic bile duct epithelial neoplasm. Cellosaurus records it as misclassified. 83 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. SK-HEP-1. Cell lines, record CVCL_0525. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0525
On this page
Cell line
As Cellosaurus gives it.
- Name
- SK-HEP-1
- Accession
- CVCL_0525
- RRID
- RRID:CVCL_0525
- Synonyms
- SK-Hep-1, SK HEP-1, SK HEP 01, SK-Hep1, Sk-Hep1, SK Hep 1, SK Hep1, SKHEP-1, SKHEP1, SKHep1, SK_HEP1
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 52Y
- Category
- Cancer cell line
- Diseases
- Liver and intrahepatic bile duct epithelial neoplasm (NCIt C7106)
- Derived from
- Ascites (metastatic)
- Cell type
- Endothelial cell
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Misclassified | Originally described as originating from an adenocarcinoma of liver and thus classified as hepatocellular carcinoma. Later studies show that it most probably has arisen from endothelial cells (PubMed=1371504; PubMed=31938418). |
Source Cellosaurus
Papers83
1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Multi-omics-driven personalized management of advanced HCC. | Cell Rep Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| USP4-Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC. | Adv Sci (Weinh) | 2026 | Its Methods give the RRID and name the line | PubMed | |
| A trifluoromethyl quinazoline inhibits hepatocellular carcinoma proliferation through HDAC1 binding and multi-target mechanisms. | iScience | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Single- and dual-target CAR-T cells targeting HBsAg and GPC3 to balance safety and antitumor efficacy in HBV-positive hepatocellular carcinoma. | iScience | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory. | Cell Rep Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| IL-15 and IL-21 synergy improves anti-tumor efficacy of iPSC-derived cytotoxic T cells in solid tumors. | Mol Ther | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Synthesis of 2-Aryl(alkyl)benzimidazole Hydroxamic Acids as HDAC Inhibitors with Anti-Angiogenesis Properties. | ChemMedChem | 2026 | Its Methods give the RRID and name the line | PubMed | |
| An SLCO2B1 mRNA Isoform Acts as a Noncoding RNA to Drive Cancer Progression by Triggering Protein Biosynthesis. | Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed | |
| EP300 promotes hepatocellular carcinoma proliferation, migration and in vivo tumorigenicity revealed by integrated experimental and bioinformatic analyses. | J Transl Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| TGFβ1 Activates Lnc-APUE to Promote Tumor Metastasis via the Alu Element-Driven STAU1-Mediated Decay of CDH1 mRNA. | Adv Sci (Weinh) | 2026 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 83
See all 83 papersRelatives23
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Derived from it | Abcam SK-HEP-1 S1PR1 KO | CVCL_E7C3 | Has a recorded problem | Cell lines |
| Derived from it | F2.4E5 | CVCL_A040 | Has a recorded problem | Cell lines |
| Derived from it | F2.5B6 | CVCL_A041 | Has a recorded problem | Cell lines |
| Derived from it | HyCyte SK-HEP-1 KO-hHSP90AA1 | CVCL_E1MT | Has a recorded problem | Cell lines |
| Derived from it | HyCyte SK-HEP-1 KO-hMGST1 | CVCL_E1MU | Has a recorded problem | Cell lines |
| Derived from it | HyCyte SK-HEP-1 KO-hPFDN2 | CVCL_E1MV | Has a recorded problem | Cell lines |
| Derived from it | P1.1A3 | CVCL_A042 | Has a recorded problem | Cell lines |
| Derived from it | P1.4D6 | CVCL_A046 | Has a recorded problem | Cell lines |
| Derived from it | SK-HEP-1-Cas9-726 | CVCL_XD84 | Has a recorded problem | Cell lines |
| Derived from it | SK-HEP-1-Cas9-727 | CVCL_XD85 | Has a recorded problem | Cell lines |
1 to 10 of 23
See all 23 relativesCell banks10
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| ATCC | HTB-52 | ATCC | |
| CCTCC | GDC0145 | Cellosaurus | |
| CLS | 300334 | CLS | |
| CancerTools | 161934 | CancerTools | |
| DSMZ | ACC-141 | DSMZ | |
| ECACC | 91091816 | ECACC | |
| ICLC | HTL10001 | ICLC | |
| KCB | KCB 2013038YJ | Cellosaurus | |
| KCLB | 30052 | KCLB | |
| Ubigene | YC-C007 | Ubigene |
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_0525
GET https://conductscience.org/api/cell-lines/v1/CVCL_0525/papers?page=2