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Cell line · CVCL_0527

SK-MEL-5

Cancer cell line, Homo sapiens. Cutaneous melanoma. 80 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. SK-MEL-5. Cell lines, record CVCL_0527. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0527

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Cell line

As Cellosaurus gives it.

Name
SK-MEL-5
Accession
CVCL_0527
RRID
RRID:CVCL_0527
Synonyms
SK-Mel-5, SK MEL 5, SK.MEL.5, SK-MEL5, SKMel-5, SKMEL-5, SKMEL5, SKMel5, SKmel5, AA-Mel
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
24Y
Category
Cancer cell line
Diseases
Cutaneous melanoma (NCIt C3510)
Derived from
Axillary lymph node (metastatic)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers80

PaperJournalYearHow we knowRetractedSource
BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer-Associated Fibroblasts Crosstalk.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
αvβ3 CAR-T Cells Simultaneously Targeting Tumor and Metastases Produce Highly Effective Control in Preclinical Models of Melanoma and Triple-Negative Breast Cancer.Mol Cancer Ther2026Its Methods give the RRID and name the linePubMed
A MERTK-Targeting Antibody-Drug Conjugate Selectively Depletes M2 Tumor-Associated Macrophages and MERTK-Expressing Cancer Cells.Cancer Res2026Its Methods give the RRID and name the linePubMed
PAX3 Regulatory Signatures and Gene Targets in Melanoma Cells.Genes (Basel)2025Its Methods give the RRID and name the linePubMed
TRPM8 levels determine tumor vulnerability to channel agonists.Mol Oncol2025Its Methods give the RRID and name the linePubMed
Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration.Cancer Res2025Its Methods give the RRID and name the linePubMed
HTS384 NCI60: The Next Phase of the NCI60 Screen.Cancer Res2024Cellosaurus cites it, and its Methods give the RRID and name the linePubMed
Susceptibility of Melanoma Cells to Targeted Therapy Correlates with Protection by Blood Neutrophils.Cancers (Basel)2024Its Methods give the RRID and name the linePubMed
Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators.Sci Adv2024Its Methods give the RRID and name the linePubMed
HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression.NAR Cancer2024Its Methods give the RRID and name the linePubMed

1 to 10 of 80

See all 80 papers

Relatives1

RelationCell lineAccessionProblem
Derived from itSKMEL5/RCVCL_IW12

Source Cell lines

Cell banks6

Cell bankCatalog numberStatusSource
ATCCHTB-70ATCC
CLS300157CLS
CancerTools161920CancerTools
ICLCHTL01023ICLC
KCLB30070KCLB
NCI-DCTDSK-MEL-5Cellosaurus

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0527

GET https://conductscience.org/api/cell-lines/v1/CVCL_0527/papers?page=2