Cell line · CVCL_0588

ZR-75-1

Cancer cell line, Homo sapiens. Invasive breast carcinoma of no special type. 110 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. ZR-75-1. Cell lines, record CVCL_0588. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0588

On this page

Cell line

As Cellosaurus gives it.

Name: ZR-75-1
Accession: CVCL_0588
RRID: RRID:CVCL_0588
Synonyms: Zr-75-1, ZR751, ZR75-1, ZR75.1, ZR75_1
Species: Homo sapiens (Human)
Sex: Female
Age at sampling: 63Y
Category: Cancer cell line
Diseases: Invasive breast carcinoma of no special type (NCIt C4194)
Derived from: Ascites (metastatic)
Entry created: 2012-04-04
Entry updated: 2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers110

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
Divergent transcriptional programs and constrained metabolic states reveal selective metabolic dependencies in chemoresistant luminal breast cancer.	Cancer Drug Resist	2026	Its Methods give the RRID and name the line	PubMed
Inhibition of HOX/PBX Dimers as a Potential Therapeutic Strategy in Breast Cancer Subtypes Including Triple Negative Breast Cancer.	Curr Issues Mol Biol	2026	Its Methods give the RRID and name the line	PubMed
CDK8/19 inhibition prevents adaptive resistance to CDK4/6 inhibitors in vitro and in vivo.	Cell Rep Med	2026	Its Methods give the RRID and name the line	PubMed
Framework for evaluating in vitro vasculogenic mimicry using structural and metabolic parameters.	Cell Rep Methods	2026	Its Methods give the RRID and name the line	PubMed
Inhibition of cyclin-dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation.	Mol Oncol	2026	Its Methods give the RRID and name the line	PubMed
Expression of HER2 in the eye and the potential for on-target side effects with antibody-drug conjugates.	Sci Rep	2026	Its Methods give the RRID and name the line	PubMed
Quantification of Antibody-Drug Conjugate Targets in Head and Neck Squamous Cell Carcinoma.	Mol Cancer Ther	2026	Its Methods give the RRID and name the line	PubMed
Discovery of novel circular RNAs of the apoptosis-related BAX gene in breast cancer, by combining nanopore and next-generation sequencing.	Mol Genet Genomics	2026	Its Methods give the RRID and name the line	PubMed
Combinatorial inhibition of IGF2BP3-regulated receptor tyrosine kinases offers a new therapeutic strategy for triple-negative breast cancer.	J Exp Clin Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
TPP-45142-an Anti-HER2 T-cell Engager-Designed for Selective HER2-Low Cancer Immunotherapy.	Mol Cancer Ther	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 110

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Relatives124

Relation	Cell line	Accession	Problem	Source
Derived from it	Ubigene ZR-75-1 CEBPA KO	CVCL_E1F8		Cell lines
Derived from it	Ubigene ZR-75-1 CEBPB KO	CVCL_E1F9		Cell lines
Derived from it	Ubigene ZR-75-1 LDHA KO	CVCL_E1FA		Cell lines
Derived from it	Ubigene ZR-75-1 RNF20 KO	CVCL_E1FB		Cell lines
Derived from it	Ubigene ZR-75-1 SATB1 KO	CVCL_E1FC		Cell lines
Derived from it	Ubigene ZR-75-1 SLC25A38 KO	CVCL_E1FD		Cell lines
Derived from it	YMB-1	CVCL_2814	Has a recorded problem	Cell lines
Derived from it	ZR-75-1 AKT1 pool B	CVCL_E4WR		Cell lines
Derived from it	ZR-75-1 AKT2 pool B	CVCL_E4WS		Cell lines
Derived from it	ZR-75-1 BCAR1 clone 4A12	CVCL_E4WT		Cell lines

1 to 10 of 124

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Cell banks13

Cell bank	Catalog number	Source
ATCC	CRL-1500	ATCC
AddexBio	C0006011/4901	Cellosaurus
BCRC	60055	BCRC
CLS	300163	CLS
CancerTools	154547	CancerTools
ECACC	87012601	ECACC
IBRC	C10099	Cellosaurus
ICLC	HTL99006	ICLC
IZSLER	BS TCL 75	Cellosaurus
KCB	KCB 2010136YJ	Cellosaurus

1 to 10 of 13

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Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0588

GET https://conductscience.org/api/cell-lines/v1/CVCL_0588/papers?page=2

API reference For AI assistants