Cell line · CVCL_0594

NIH 3T3

Spontaneously immortalized cell line, Mus musculus. 264 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. NIH 3T3. Cell lines, record CVCL_0594. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_0594

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Cell line

As Cellosaurus gives it.

Name: NIH 3T3
Accession: CVCL_0594
RRID: RRID:CVCL_0594
Synonyms: NIH/3T3, NIH-3T3, NIH3T3, 3T3, 3T3NIH, 3T3-Swiss, Swiss-3T3, Swiss/3T3, Swiss 3T3, Swiss3T3
Species: Mus musculus (Mouse)
Sex: Male
Age at sampling: Embryo
Category: Spontaneously immortalized cell line
Derived from: Whole embryo (in situ)
Cell type: Fibroblast
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers264

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
Directionally aligned nanofibrous polycaprolactone/gelatin scaffolds as durable scleral implants for long‐term ocular reconstruction	Bioeng Transl Med	2026	Its Methods give the RRID and name the line	PubMed
Exploring Chemical Diversity Alongside Antioxidant, Antimicrobial, Antiproliferative, Anti-Inflammatory, and Caenorhabditis elegans Locomotor Responses in Whole, Caps and Stipes of Suillus luteus and Agaricus bisporus.	Pharmaceuticals (Basel)	2026	Its Methods give the RRID and name the line	PubMed
Fridericia chica standardized extract combined with tocotrienol-enriched fraction from Bixa orellana promotes gastric mucosal protection: in vitro combination selection and in vivo evaluation.	Pharm Biol	2026	Its Methods give the RRID and name the line	PubMed
Mechanism of activation of an ancestral TEC kinase by PIP3.	Npj Struct Biol	2026	Its Methods give the RRID and name the line	PubMed
Aberrant Accumulation of Cyclin D1 Rewires Glutamine Metabolism and Generates a Metabolic Vulnerability in Squamous Cell Carcinoma.	Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
In Situ Genetic Engineering Facilitates MMP-9-Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf-1/ERK1/2/PINK1 Signaling Axis.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Antitumor-Relevant Evaluation of Liquid and Microencapsulated Lepidium meyenii and Bactris gasipaes Extracts Reveals Species- and Formulation-Dependent Activity.	Molecules	2026	Its Methods give the RRID and name the line	PubMed
MORC1 coordinates TRIM28 interaction and nuclear condensate formation for transposon silencing.	iScience	2026	Its Methods give the RRID and name the line	PubMed
Paclitaxel induces NM2-dependent cellular contraction through GEF-H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells.	Mol Oncol	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 264

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Relatives180

Relation	Cell line	Accession	Source
Derived from it	3J1	CVCL_M056	Cell lines
Derived from it	3T3 rho-0#8	CVCL_YY06	Cell lines
Derived from it	3T3-mB7-H4	CVCL_A0VH	Cell lines
Derived from it	3T3-msCD40L	CVCL_1H10	Cell lines
Derived from it	3T3.T4	CVCL_1E11	Cell lines
Derived from it	A4 [Mouse]	CVCL_F962	Cell lines
Derived from it	ANN-1	CVCL_9242	Cell lines
Derived from it	Abeomics NIH 3T3 C3aR1	CVCL_D7C7	Cell lines
Derived from it	Ampli-GPE	CVCL_4104	Cell lines
Derived from it	B104-1-1	CVCL_0396	Cell lines

1 to 10 of 180

See all 180 relatives

Cell banks23

Cell bank	Catalog number	Status	Source
ABM	T8981		ABM
ATCC	CRL-1658		ATCC
ATCC	CRL-6442	Discontinued	Cellosaurus
AddexBio	P0011001/83		Cellosaurus
BCRC	60008		BCRC
BCRJ	0191		BCRJ
BEI_Resources	ARP-9946		BEI_Resources
CCLV	CCLV-RIE 0058		Cellosaurus
CCTCC	GDC0030		Cellosaurus
CLS	400101		CLS

1 to 10 of 23

See all 23 cell banks

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_0594

GET https://conductscience.org/api/cell-lines/v1/CVCL_0594/papers?page=2

API reference For AI assistants