Cell line · CVCL_1281
HLE
Cancer cell line, Homo sapiens. Adult hepatocellular carcinoma. 36 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. HLE. Cell lines, record CVCL_1281. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1281
On this page
Cell line
As Cellosaurus gives it.
- Name
- HLE
- Accession
- CVCL_1281
- RRID
- RRID:CVCL_1281
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 68Y
- Category
- Cancer cell line
- Diseases
- Adult hepatocellular carcinoma (NCIt C7956); Adult hepatocellular carcinoma (ORDO Orphanet_210159)
- Derived from
- Liver (in situ)
- Cell type
- Epithelial cell
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Caution | TP53 mutation indicated incorrectly as being at c.747G>T in PubMed=8389256. |
Source Cellosaurus
Papers36
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Morpholino-mediated splice switching of NELFE suppresses hepatocellular carcinoma cell phenotypes in vitro and in vivo. | Mol Ther Nucleic Acids | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Subtype-dependent PD-L1 stability and immune context shape immunotherapy response in hepatocellular carcinoma. | Front Immunol | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma. | Int J Cancer | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Dual Roles of Canagliflozin on Cholangiocarcinoma Cell Growth and Enhanced Growth Suppression in Combination with FK866. | Int J Mol Sci | 2025 | Its Methods give the RRID and name the line | PubMed | |
| HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma. | Cancer Res | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Tracking fructose 1,6-bisphosphate dynamics in liver cancer cells using a fluorescent biosensor. | iScience | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Pan-cancer proteomic map of 949 human cell lines. | Cancer Cell | 2022 | Cellosaurus cites it | PubMed | |
| RNA Sequencing of Hepatobiliary Cancer Cell Lines: Data and Applications to Mutational and Transcriptomic Profiling. | Cancers (Basel) | 2020 | Cellosaurus cites it | PubMed | |
| The Effect of Methylselenocysteine and Sodium Selenite Treatment on microRNA Expression in Liver Cancer Cell Lines. | Pathol Oncol Res | 2020 | Its Methods give the RRID and name the line | PubMed | |
| A Pharmacogenomic Landscape in Human Liver Cancers. | Cancer Cell | 2019 | Cellosaurus cites it | PubMed |
1 to 10 of 36
See all 36 papersRelatives3
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Derived from it | HLE-LUC | CVCL_JF92 | Cell lines | |
| Derived from it | HLE/2E1 | CVCL_X149 | Cell lines | |
| From the same person | HLF | CVCL_2947 | Cell lines |
Cell banks1
| Cell bank | Catalog number | Status |
|---|---|---|
| JCRB | JCRB0404 |
Source JCRB
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1281
GET https://conductscience.org/api/cell-lines/v1/CVCL_1281/papers?page=2