Cell line · CVCL_1288

HSC-3

Cancer cell line, Homo sapiens. Tongue squamous cell carcinoma. 67 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. HSC-3. Cell lines, record CVCL_1288. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1288

On this page

Cell line

As Cellosaurus gives it.

Name: HSC-3
Accession: CVCL_1288
RRID: RRID:CVCL_1288
Synonyms: HSC 3, HSC3
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 64Y
Category: Cancer cell line
Diseases: Tongue squamous cell carcinoma (NCIt C4648); Squamous cell carcinoma of the oral tongue (ORDO Orphanet_457252)
Derived from: Cervical lymph node (metastatic)
Entry created: 2012-04-04
Entry updated: 2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers67

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
NLRX1 contributes to immunotherapeutic resistance of head and neck squamous cell carcinoma by suppressing type I interferon pathway.	Front Immunol	2026	Its Methods give the RRID and name the line	PubMed
SLC15A4 promotes oral cancer progression by regulating TLR9 and activating the JAK/STAT signaling pathway.	Head Face Med	2026	Its Methods give the RRID and name the line	PubMed
Maackia amurensis seed lectin inhibits oral squamous cell carcinoma tumorigenesis by suppressing N6-methyladenosine modification-mediated SRY-box transcription factor 2 expression.	J Int Med Res	2026	Its Methods give the RRID and name the line	PubMed
ENOX2 (tNOX)-Associated Stemness in Oral Cancer Cells and Its Clinical Correlation in Head and Neck Tumors.	Antioxidants (Basel)	2026	Its Methods give the RRID and name the line	PubMed
Distinct Regulation of the ARF and TAp73 Tumor Suppressor Genes by the Transcription Factor E2F1 Enables Discrimination of Cancer Cells from Normal Growing Cells.	Cells	2026	Its Methods give the RRID and name the line	PubMed
Tempeh Extract and HSC-3 Cell Migration: An In Vitro Study.	Asian Pac J Cancer Prev	2025	Its Methods give the RRID and name the line	PubMed
Quantitative and longitudinal monitoring of cancer cell invasion in a three-dimensional in vitro model of oral cancer using optical coherence tomography.	Sci Rep	2025	Its Methods give the RRID and name the line	PubMed
Therapeutic stress triggers tumor STAT1 acetylation to disarm immunotherapy.	Cell Rep Med	2025	Its Methods give the RRID and name the line	PubMed
Mortalin Represents a Promising Therapeutic Target for Oral Cancers: Clinical Relevance and Experimental Evidence for the Activation of Akt/mTOR Signaling.	Cancers (Basel)	2025	Its Methods give the RRID and name the line	PubMed
In vitro assessment of BBI608 in 2D and 3D culture models for drug repositioning in oral squamous cell carcinoma.	Oncol Rep	2025	Its Methods give the RRID and name the line	PubMed

1 to 10 of 67

See all 67 papers

Relatives7

Relation	Cell line	Accession	Source
Derived from it	HSC-3-M3	CVCL_8323	Cell lines
Derived from it	HSC-3/CMV-Luc	CVCL_JF94	Cell lines
Derived from it	HSC3/hPDPN	CVCL_YA14	Cell lines
Derived from it	LMF3	CVCL_W514	Cell lines
Derived from it	LMF4	CVCL_W515	Cell lines
Derived from it	LMF5	CVCL_W516	Cell lines
Derived from it	Ubigene HSC-3 IGF2BP2 KO	CVCL_D9WC	Cell lines

Cell banks6

Cell bank	Catalog number	Source
CLS	305312	CLS
JCRB	JCRB0623	JCRB
Millipore	SCC193	Millipore
RCB	RCB1975	RCB
TKG	TKG 0484	Cellosaurus
Ubigene	YC-C063	Ubigene

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1288

GET https://conductscience.org/api/cell-lines/v1/CVCL_1288/papers?page=2

API reference For AI assistants