Cell line · CVCL_1289
HSC-4
Cancer cell line, Homo sapiens. Tongue squamous cell carcinoma. 46 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. HSC-4. Cell lines, record CVCL_1289. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1289
On this page
Cell line
As Cellosaurus gives it.
- Name
- HSC-4
- Accession
- CVCL_1289
- RRID
- RRID:CVCL_1289
- Synonyms
- HSC4
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 64Y
- Category
- Cancer cell line
- Diseases
- Tongue squamous cell carcinoma (NCIt C4648); Squamous cell carcinoma of the oral tongue (ORDO Orphanet_457252)
- Derived from
- Cervical lymph node (metastatic)
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers46
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Genome-wide CRISPR screen identifies AMBRA1 as a potential biomarker of response to platinum-based therapies in oral squamous cell carcinomas. | iScience | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Matrix Stiffness Drives Aggressive Phenotype in Tongue Squamous Cell Carcinoma via Mechanotransduction-Stromal Signalling. | Int Dent J | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Aberrant Hippo-YAP/TEAD Signaling Drives Malignant Transcriptional Reprogramming in External Auditory Canal Squamous Cell Carcinoma. | Cancer Res Commun | 2026 | Its Methods give the RRID and name the line | PubMed | |
| LMO4 promotes OSCC progression by inducing RAB17 degradation and ferroptosis resistance. | Cell Death Dis | 2025 | Its Methods give the RRID and name the line | PubMed | |
| In vitro assessment of BBI608 in 2D and 3D culture models for drug repositioning in oral squamous cell carcinoma. | Oncol Rep | 2025 | Its Methods give the RRID and name the line | PubMed | |
| EGFRvIII-driven microenvironmental fibroblast activation and transformation accelerate oral cancer progression via lipocalin-2/STAT3 axis. | Neoplasia | 2025 | Its Methods give the RRID and name the line | PubMed | |
| The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments. | Mol Oncol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Targeting ferroptosis for improved radiotherapy outcomes in HPV-negative head and neck squamous cell carcinoma. | Mol Oncol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| TNO155 is a selective SHP2 inhibitor to target PTPN11-dependent oral squamous cell carcinoma. | Heliyon | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Development and Characterization of a Three-Dimensional Organotypic In Vitro Oral Cancer Model with Four Co-Cultured Cell Types, Including Patient-Derived Cancer-Associated Fibroblasts. | Biomedicines | 2024 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 46
See all 46 papersRelatives0
None in this release.
Cell banks3
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| JCRB | JCRB0624 | JCRB | |
| RCB | RCB1902 | RCB | |
| TKG | TKG 0489 | Cellosaurus |
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1289
GET https://conductscience.org/api/cell-lines/v1/CVCL_1289/papers?page=2