Cell line · CVCL_1509
NCI-H196
Cancer cell line, Homo sapiens. Lung sarcomatoid carcinoma. 36 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. NCI-H196. Cell lines, record CVCL_1509. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1509
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Cell line
As Cellosaurus gives it.
- Name
- NCI-H196
- Accession
- CVCL_1509
- RRID
- RRID:CVCL_1509
- Synonyms
- H196, H-196, NCIH196
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 68Y
- Category
- Cancer cell line
- Diseases
- Lung sarcomatoid carcinoma (NCIt C45540)
- Derived from
- Pleural effusion (metastatic)
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Caution | Originally classified as originating from a lung small cell carcinoma, but is reclassified as a lung sarcomatoid carcinoma based on a number of criteria (PubMed=38180245). |
Source Cellosaurus
Papers36
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| TNIK Overexpression Is Sufficient for Chemoradiation Resistance in Limited-Stage Small Cell Lung Cancer. | Mol Cancer Ther | 2026 | Its Methods give the RRID and name the line | PubMed | |
| KDM7B-mediated demethylation of RNF113A regulates small cell lung cancer sensitivity to alkylation damage. | bioRxiv | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Engineering tandem VHHs to target different epitopes to enhance antibody-dependent cell-mediated cytotoxicity. | FEBS Open Bio | 2026 | Its Methods give the RRID and name the line | PubMed | |
| DNA-PK inhibition sustains the antitumor innate immune response in small cell lung cancer. | iScience | 2025 | Its Methods give the RRID and name the line | PubMed | |
| The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer. | Int J Mol Sci | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Noncanonical inhibition of topoisomerase II alpha by oxidative stress metabolites. | Redox Biol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Sympathetic Neurons Promote Small Cell Lung Cancer through the β2-Adrenergic Receptor. | Cancer Discov | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer. | Cell Rep Med | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Combination screen in multi-cell type tumor spheroids reveals interaction between aryl hydrocarbon receptor antagonists and E1 ubiquitin-activating enzyme inhibitor. | SLAS Discov | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies. | Clin Cancer Res | 2024 | Cellosaurus cites it, and its Methods give the RRID and name the line | PubMed |
1 to 10 of 36
See all 36 papersRelatives0
None in this release.
Cell banks3
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| ATCC | CRL-5823 | ATCC | |
| CLS | 300390 | CLS | |
| KCLB | 90196 | Discontinued | Cellosaurus |
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1509
GET https://conductscience.org/api/cell-lines/v1/CVCL_1509/papers?page=2