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Cell line · CVCL_1517

NCI-H2030

Cancer cell line, Homo sapiens. Lung adenocarcinoma. 38 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. NCI-H2030. Cell lines, record CVCL_1517. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1517

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Cell line

As Cellosaurus gives it.

Name
NCI-H2030
Accession
CVCL_1517
RRID
RRID:CVCL_1517
Synonyms
H2030, H-2030, NCIH2030
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
Age unspecified
Category
Cancer cell line
Diseases
Lung adenocarcinoma (NCIt C3512)
Derived from
Lymph node (metastatic)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers38

PaperJournalYearHow we knowRetractedSource
Amphiregulin-mediated EGFR activation drives both intrinsic and acquired resistance to KRAS G12C inhibitors in KRAS G12C-mutant non-small cell lung cancer.Oncogene2026Its Methods give the RRID and name the linePubMed
HES1 inhibition overcomes CDK4/6 inhibitor resistance by targeting cancer stemness in lung adenocarcinoma.J Exp Clin Cancer Res2026Its Methods give the RRID and name the linePubMed
Targeting KRAS Codon 13 Mutations Using Direct Combination Approaches in Non-Small Cell Lung Cancer.Cancer Discov2026Its Methods give the RRID and name the linePubMed
Characterization and therapeutic suppression of KEAP1-NRF2-driven resistance to KRAS inhibitors in pancreatic and lung cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed
ANP32A-mediated histone 3 K27 acetylation is essential for sotorasib activity in KRAS-mutant non-small cell lung cancer.J Biol Chem2026Its Methods give the RRID and name the linePubMed
CD146+ pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis.Theranostics2026Its Methods give the RRID and name the linePubMed
Epigenetic Regulation of Chromosomal Instability by EZH2 Methyltransferase.Cancer Discov2026Its Methods give the RRID and name the linePubMed
PLK1-mediated PDHA1 phosphorylation drives mitochondrial dysfunction, mitophagy, and cancer progression in Cr(VI)-associated lung cancer.J Biol Chem2025Its Methods give the RRID and name the linePubMed
The Selective WEE1 Inhibitor Azenosertib Shows Synergistic Antitumor Activity with KRASG12C Inhibitors in Preclinical Models.Cancer Res Commun2025Its Methods give the RRID and name the linePubMed
Impact of Co-mutations and Transcriptional Signatures in Non-Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial.Clin Cancer Res2025Its Methods give the RRID and name the linePubMed

1 to 10 of 38

See all 38 papers

Relatives1

RelationCell lineAccessionProblem
Derived from itH2030-TGLCVCL_XA21

Source Cell lines

Cell banks2

Cell bankCatalog numberStatusSource
ATCCCRL-5914ATCC
HysigenTCH-C488Hysigen

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1517

GET https://conductscience.org/api/cell-lines/v1/CVCL_1517/papers?page=2