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Cell line · CVCL_1535

NCI-H2170

Cancer cell line, Homo sapiens. Lung squamous cell carcinoma. 37 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. NCI-H2170. Cell lines, record CVCL_1535. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1535

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Cell line

As Cellosaurus gives it.

Name
NCI-H2170
Accession
CVCL_1535
RRID
RRID:CVCL_1535
Synonyms
H2170, H-2170, NCIH2170
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
Age unspecified
Category
Cancer cell line
Diseases
Lung squamous cell carcinoma (NCIt C3493)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers37

PaperJournalYearHow we knowRetractedSource
AXL-SHC1 signaling axis mediates adaptive resistance to HER2-targeted tyrosine kinase inhibitors in HER2-aberrant lung and gastric cancers.NPJ Precis Oncol2026Its Methods give the RRID and name the linePubMed
Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
E2A selectively regulates TGF-β-induced apoptosis in KRAS-mutant non-small cell lung cancer.Mol Oncol2026Its Methods give the RRID and name the linePubMed
Loss of Payload Sensitivity and Other Mechanisms of Resistance to T-DXd in HER2-Mutant NSCLC: Implications for Subsequent Responsiveness to HER2 TKIs.J Thorac Oncol2026Its Methods give the RRID and name the linePubMed
Macropinocytosis and Vascularization Determine Response to mTOR Inhibitors in Lung Squamous Cell Carcinoma.Cancer Res2026Its Methods give the RRID and name the linePubMed
Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer.Cancer Discov2026Its Methods give the RRID and name the linePubMed
HACD3 promotes malignant progression of NSCLC by suppressing the MKK7/MAPK10 signaling axis.BMC Cancer2025Its Methods give the RRID and name the linePubMed
Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression.Cancer Res2025Its Methods give the RRID and name the linePubMed
Targeting AKR1B10 by Drug Repurposing with Epalrestat Overcomes Chemoresistance in Non-Small Cell Lung Cancer Patient-Derived Tumor Organoids.Clin Cancer Res2024Its Methods give the RRID and name the linePubMed
FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling.Mol Oncol2024Its Methods give the RRID and name the linePubMed

1 to 10 of 37

See all 37 papers

Relatives0

None in this release.

Cell banks4

Cell bankCatalog numberStatusSource
ATCCCRL-5928ATCC
AddexBioC0016018/4970Cellosaurus
BCRJ0271BCRJ
CLS305276CLS

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1535

GET https://conductscience.org/api/cell-lines/v1/CVCL_1535/papers?page=2