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Cell line · CVCL_1544

NCI-H226

Cancer cell line, Homo sapiens. Pleural epithelioid mesothelioma. 87 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. NCI-H226. Cell lines, record CVCL_1544. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1544

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Cell line

As Cellosaurus gives it.

Name
NCI-H226
Accession
CVCL_1544
RRID
RRID:CVCL_1544
Synonyms
NCI.H226, NCI H226, H226, H-226, HUT-226, HUT 226, NCIH226
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
Age unspecified
Category
Cancer cell line
Diseases
Pleural epithelioid mesothelioma (NCIt C45662); Pleural mesothelioma (ORDO Orphanet_50251)
Derived from
Pleural effusion (in situ)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems1

ProblemCellosaurus's note
CautionIndicated to have a TP53 p.Arg158Leu (c.473G>T) mutation according to PubMed=1311061, but no TP53 mutation detected according to PubMed=20557307, CCLE and Cosmic-CLP.

Papers87

PaperJournalYearHow we knowRetractedSource
KLF4 Promotes a KRT13+ Hillock-Like State in Lung Squamous Cell Carcinoma.Cancer Res2026Its Methods give the RRID and name the linePubMed
Protein phosphatase 2 phosphatase activator (PTPA) promotes oncogene-induced senescence and carboplatin response in human malignant pleural mesothelioma cells.Cell Oncol (Dordr)2026Its Methods give the RRID and name the linePubMed
Do G4 ligands induce mitochondrial dysfunction without ROS induction.iScience2026Its Methods give the RRID and name the linePubMed
MPND Loss Epigenetically Activates TGFβ/SMAD3 Signaling to Drive Tumor Progression and Metastasis in Non-Small Cell Lung Cancer.Cancer Res2026Its Methods give the RRID and name the linePubMed
S6K1 Modulates STAT3 Activation to Promote Resistance to Radiotherapy in Lung Cancer.Int J Mol Sci2026Its Methods give the RRID and name the linePubMed
GM-CSF Armed Oncolytic Adenovirus Enhances T-Cell Infiltration and Suppresses Local and Distal Tumor Growth.Viruses2026Its Methods give the RRID and name the linePubMed
Anti-PD-1 Nanobody-Armored MSLN CAR-T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
HACD3 promotes malignant progression of NSCLC by suppressing the MKK7/MAPK10 signaling axis.BMC Cancer2025Its Methods give the RRID and name the linePubMed
Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells.Mol Syst Biol2025Its Methods give the RRID and name the linePubMed
Tumor cell-intrinsic circular RNA circFNDC3B attenuates CD8+ T cells infiltration in non-small cell lung cancer.Commun Biol2025Its Methods give the RRID and name the linePubMed

1 to 10 of 87

See all 87 papers

Relatives2

RelationCell lineAccessionProblemSource
Derived from itNCI-H226BrCVCL_AX73Cell lines
Derived from itNCI-H226bCVCL_VK08Cell lines

Cell banks5

Cell bankCatalog numberStatusSource
ATCCCRL-5826ATCC
AddexBioC0016011/4916Cellosaurus
CLS305091CLS
KCLB90226DiscontinuedCellosaurus
NCI-DCTDNCI-H226Cellosaurus

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1544

GET https://conductscience.org/api/cell-lines/v1/CVCL_1544/papers?page=2