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Cell line · CVCL_1561

NCI-H441

Cancer cell line, Homo sapiens. Lung papillary adenocarcinoma. 67 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. NCI-H441. Cell lines, record CVCL_1561. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1561

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Cell line

As Cellosaurus gives it.

Name
NCI-H441
Accession
CVCL_1561
RRID
RRID:CVCL_1561
Synonyms
H441, H-441, NCI-H441-4, NCI-441, NCIH441
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
33Y
Category
Cancer cell line
Diseases
Lung papillary adenocarcinoma (NCIt C5650)
Derived from
Pericardial effusion (metastatic)
Cell type
Club cell
Entry created
2012-04-04
Entry updated
2025-08-14

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers67

PaperJournalYearHow we knowRetractedSource
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription.FEBS Open Bio2026Its Methods give the RRID and name the linePubMed
Biomolecular Condensates as Protein Degradation Tools for Intracellular Targets.Nat Commun2026Its Methods give the RRID and name the linePubMed
Inhibition of LIMK by Cofilin-1 peptidomimetics enhances actin depolymerization and reduces metastasis of non-small cell lung cancer.Oncogenesis2026Its Methods give the RRID and name the linePubMed
Characterization and therapeutic suppression of KEAP1-NRF2-driven resistance to KRAS inhibitors in pancreatic and lung cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed
Tumor-Derived Complement C3 Overexpression in STK11-Mutant Lung Adenocarcinoma Drives Tumor Growth and Immune Checkpoint Inhibitor Resistance.Cancer Immunol Res2026Its Methods give the RRID and name the linePubMed
Antibodies blocking PlGF or VEGF interactions with the NRP1 receptor mediate antiproliferative effects.J Biol Chem2026Its Methods give the RRID and name the linePubMed
KRASG12V/HLA-A*02:01-targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors.Sci Adv2026Its Methods give the RRID and name the lineRetractedPubMed
Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates.Nat Commun2026Its Methods give the RRID and name the linePubMed
Sym024 Interacts with a Unique Epitope on the CD73 Homodimer, Favoring Effective Bivalent Binding to Improve Anti-PD-1 Therapy.Clin Cancer Res2026Its Methods give the RRID and name the linePubMed
Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling.J Med Chem2026Its Methods give the RRID and name the linePubMed

1 to 10 of 67

See all 67 papers

Relatives1

RelationCell lineAccessionProblem
Derived from itNCI-H441/CMV-LucCVCL_M254

Source Cell lines

Cell banks8

Cell bankCatalog numberStatusSource
ATCCCRM-HTB-174ATCC
ATCCHTB-174ATCC
AddexBioC0016019/4975Cellosaurus
BCRC60455BCRC
BCRJ0359BCRJ
CCTCCGDC0308Cellosaurus
CLS305219CLS
IZSLERBS TCL 215Cellosaurus

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1561

GET https://conductscience.org/api/cell-lines/v1/CVCL_1561/papers?page=2