Cell line · CVCL_1577
NCI-H661
Cancer cell line, Homo sapiens. Lung large cell carcinoma. 42 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. NCI-H661. Cell lines, record CVCL_1577. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1577
On this page
Cell line
As Cellosaurus gives it.
- Name
- NCI-H661
- Accession
- CVCL_1577
- RRID
- RRID:CVCL_1577
- Synonyms
- H661, H-661, NCIH661
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 43Y
- Category
- Cancer cell line
- Diseases
- Lung large cell carcinoma (NCIt C4450)
- Derived from
- Lymph node (metastatic)
- Entry created
- 2012-04-04
- Entry updated
- 2026-06-25
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers42
1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Targeting the CHD3 chromatin remodeler exploits a synthetic lethal vulnerability in dual SMARCA4/SMARCA2-deficient cancers via derepression of PARD3B. | NPJ Precis Oncol | 2026 | Its Methods give the RRID and name the line | PubMed | |
| S6K1 Modulates STAT3 Activation to Promote Resistance to Radiotherapy in Lung Cancer. | Int J Mol Sci | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Identification and Nonclinical Characterization of SAR444200, a Novel Anti-GPC3 NANOBODY T-cell Engager, for the Treatment of GPC3+ Solid Tumors. | Mol Cancer Ther | 2026 | Its Methods give the RRID and name the line | PubMed | |
| LT1-3, a Slit2-Derived Peptide, Exhibits Anti-Tumor Activity and Improves Cisplatin Therapy. | Cells | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex. | Cancer Discov | 2025 | Its Methods give the RRID and name the line | PubMed | |
| DNA-PK inhibition sustains the antitumor innate immune response in small cell lung cancer. | iScience | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification. | Mol Cancer Ther | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer. | Cell Rep Med | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Immune-Cell-Derived Exosomes as a Potential Novel Tool to Investigate Immune Responsiveness in SCLC Patients: A Proof-of-Concept Study. | Cancers (Basel) | 2024 | Its Methods give the RRID and name the line | PubMed | |
| PBMCs as Tool for Identification of Novel Immunotherapy Biomarkers in Lung Cancer. | Biomedicines | 2024 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 42
See all 42 papersRelatives1
| Relation | Cell line | Accession | Problem |
|---|---|---|---|
| Derived from it | NCI-H661/Cas9-hyg | CVCL_C7U5 |
Source Cell lines
Cell banks6
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| ATCC | HTB-183 | ATCC | |
| BCRC | 60125 | BCRC | |
| CLS | 305085 | CLS | |
| Hysigen | TCH-C287 | Hysigen | |
| IZSLER | BS TCL 218 | Cellosaurus | |
| KCB | KCB 200823YJ | Cellosaurus |
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1577
GET https://conductscience.org/api/cell-lines/v1/CVCL_1577/papers?page=2