Cell line · CVCL_1595
NCI-H841
Cancer cell line, Homo sapiens. Thoracic SMARCA4-deficient undifferentiated tumor. 32 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. NCI-H841. Cell lines, record CVCL_1595. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1595
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Cell line
As Cellosaurus gives it.
- Name
- NCI-H841
- Accession
- CVCL_1595
- RRID
- RRID:CVCL_1595
- Synonyms
- H841, H-841, NCI-841, NCIH841
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 51Y
- Category
- Cancer cell line
- Diseases
- Thoracic SMARCA4-deficient undifferentiated tumor (NCIt C183115)
- Derived from
- Lung (in situ)
- Entry created
- 2012-04-04
- Entry updated
- 2025-08-14
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Caution | Originally classified as originating from a lung small cell carcinoma, but is reclassified as a thoracic SMARCA4-deficient undifferentiated tumor based on a number of criteria (PubMed=38180245). |
Source Cellosaurus
Papers32
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| NK cell immune fitness stratifies small cell lung cancer into four functional states associated with clinical response. | J Liq Biopsy | 2026 | Its Methods give the RRID and name the line | PubMed | |
| SCLC humanized mice identify T cell infiltration phenotypes in response to combination immune-radiation therapies. | iScience | 2026 | Its Methods give the RRID and name the line | PubMed | |
| c-JUN enhances CRISPR knockin anti-B7-H3 CAR T cell function in small cell lung cancer and thoracic SMARCA4-deficient undifferentiated tumors. | Cell Rep Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Roles of Annexin A1 Expression in Small Cell Lung Cancer. | Cancers (Basel) | 2025 | Its Methods give the RRID and name the line | PubMed | |
| The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer. | Int J Mol Sci | 2025 | Its Methods give the RRID and name the line | PubMed | |
| The Synergistic Effect of PARP Inhibitors and Irinotecan in Small Cell Lung Cancer Cells. | Cancer Res Treat | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Jumonji histone demethylases are therapeutic targets in small cell lung cancer. | Oncogene | 2024 | Cellosaurus cites it | PubMed | |
| Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies. | Clin Cancer Res | 2024 | Cellosaurus cites it, and its Methods give the RRID and name the line | PubMed | |
| Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs. | Cancer Res Commun | 2023 | Its Methods give the RRID and name the line | PubMed | |
| Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors. | Cancer Res | 2023 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 32
See all 32 papersRelatives0
None in this release.
Cell banks2
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1595
GET https://conductscience.org/api/cell-lines/v1/CVCL_1595/papers?page=2