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Cell line · CVCL_1619

OCI-AML-2

Cancer cell line, Homo sapiens. Adult acute myeloid leukemia. 39 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. OCI-AML-2. Cell lines, record CVCL_1619. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1619

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Cell line

As Cellosaurus gives it.

Name
OCI-AML-2
Accession
CVCL_1619
RRID
RRID:CVCL_1619
Synonyms
OCI/AML-2, OCIAML-2, OCI-AML2, OCI/AML2, OCI AML2, OCIAML2, AML-2, Ontario Cancer Institute-Acute Myeloid Leukemia-2
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
65Y
Category
Cancer cell line
Diseases
Adult acute myeloid leukemia (NCIt C9154); Acute myeloid leukemia with t(6;11)(q27;q23) KMT2A-MLLT4 (NCIt C132105); Acute myeloid leukemia (ORDO Orphanet_519)
Derived from
Peripheral blood (in situ)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers39

PaperJournalYearHow we knowRetractedSource
Targeting SMC3 deacetylation synergizes with XPO1 inhibition to reprogram the epigenetic landscape and suppress NPM1-mutated acute myeloid leukemia.Nat Commun2026Its Methods give the RRID and name the linePubMed
Development of CAR T Cells Targeting a Surface RNA-Binding Protein for the Treatment of Acute Leukemias.Cancer Discov2026Its Methods give the RRID and name the linePubMed
ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
Cysteine-reactive covalent chloro-N-acetamide ligands induce ferroptosis mediated cell death.EMBO Rep2025Its Methods give the RRID and name the linePubMed
Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.Cancer Discov2025Its Methods give the RRID and name the linePubMed
CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models.Cell Rep Med2025Its Methods give the RRID and name the linePubMed
Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy.Front Immunol2025Its Methods give the RRID and name the linePubMed
BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) PathwayRes Sq2025Its Methods give the RRID and name the linePubMed
Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.Mol Cancer2024Its Methods give the RRID and name the linePubMed
Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM).Blood Cancer J2024Its Methods give the RRID and name the linePubMed

1 to 10 of 39

See all 39 papers

Relatives10

RelationCell lineAccessionProblemSource
Derived from itEDITGENE OCI-AML-2-CopGFPCVCL_F6C9Cell lines
Derived from itEDITGENE OCI-AML-2-FLUCCVCL_F5USCell lines
Derived from itOU-AML-1CVCL_8391Has a recorded problemCell lines
Derived from itOU-AML-2CVCL_8392Has a recorded problemCell lines
Derived from itOU-AML-3CVCL_8393Has a recorded problemCell lines
Derived from itOU-AML-4CVCL_8394Has a recorded problemCell lines
Derived from itOU-AML-5CVCL_8395Has a recorded problemCell lines
Derived from itOU-AML-6CVCL_8396Has a recorded problemCell lines
Derived from itOU-AML-7CVCL_8397Has a recorded problemCell lines
Derived from itOU-AML-8CVCL_8398Has a recorded problemCell lines

Cell banks4

Cell bankCatalog numberStatusSource
BCRJ0383BCRJ
DSMZACC-99DSMZ
EDITGENEEDC00256EDITGENE
ICLCHTL01010ICLC

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1619

GET https://conductscience.org/api/cell-lines/v1/CVCL_1619/papers?page=2