Cell line · CVCL_1628
OVCAR-5
Cancer cell line, Homo sapiens. High grade ovarian serous adenocarcinoma. Cellosaurus records it as possibly misclassified. 84 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. OVCAR-5. Cell lines, record CVCL_1628. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1628
On this page
Cell line
As Cellosaurus gives it.
- Name
- OVCAR-5
- Accession
- CVCL_1628
- RRID
- RRID:CVCL_1628
- Synonyms
- OVCAR 5, NIH:OVCAR-5, OVCAR.5, OVCAR5, Ovcar5, OVCA5
- Species
- Homo sapiens (Human)
- Sex
- Female
- Age at sampling
- 67Y
- Category
- Cancer cell line
- Diseases
- High grade ovarian serous adenocarcinoma (NCIt C105555)
- Derived from
- Ascites (metastatic)
- Entry created
- 2012-04-04
- Entry updated
- 2026-06-25
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Possibly misclassified | Originally thought to be a high grade ovarian serous adenocarcinoma but suspected to have a upper gastrointestinal origin (PubMed=27353327). |
Source Cellosaurus
Papers84
1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas. | Mol Oncol | 2026 | Its Methods give the RRID and name the line | PubMed | |
| A First-in-Class LZK Inhibitor Suppresses Tumor Growth and Potentiates EGFR and PI3K Pathway Blockade in Head and Neck and Esophageal Cancers. | bioRxiv | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Two-step PEG-based surface functionalization of gold nanoparticles enables specific SERS imaging of EGFR in an ovarian cancer cell model. | Mater Today Bio | 2026 | Its Methods give the RRID and name the line | PubMed | |
| DNA Methyltransferase Inhibition Prevents Platinum-Induced Ovarian Cancer Stem Cell Enrichment. | Cancer Res Commun | 2026 | Its Methods give the RRID and name the line | PubMed | |
Enhanced expression of ADAMTS1 in ovarian carcinomas: loss of ADAMTS1 expression instigates cellular reprogramming of extracellular matrix ensuing altered plasticity, augmented migration and attenuated adhesion. | J Biomed Sci | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Suppression of AKT Activation through LZK Inhibition Limits Tumor Growth in Esophageal and Head and Neck Cancers. | Mol Cancer Ther | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Platelets induce VISTA expression and modulate the ovarian tumor microenvironment. | Platelets | 2026 | Its Methods give the RRID and name the line | PubMed | |
| KRASG12V/HLA-A*02:01-targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors. | Sci Adv | 2026 | Its Methods give the RRID and name the line | Retracted | PubMed |
| Dynamic and Ongoing De Novo L1 Retrotransposition Contributes to Genome Plasticity and Intrapatient Heterogeneity in Ovarian Cancer. | Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Metabolic Dependency on De Novo Pyrimidine Synthesis Is a Targetable Vulnerability in Platinum-Resistant Ovarian Cancer. | Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 84
See all 84 papersRelatives3
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Derived from it | OVCAR-5 CBPR | CVCL_E3AR | Has a recorded problem | Cell lines |
| Derived from it | OVCAR-5-CisR | CVCL_UI87 | Has a recorded problem | Cell lines |
| Derived from it | OVCAR-5/RFP | CVCL_JY85 | Has a recorded problem | Cell lines |
Cell banks3
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| CLS | 305616 | CLS | |
| Millipore | SCC259 | Millipore | |
| NCI-DCTD | OVCAR-5 | Cellosaurus |
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1628
GET https://conductscience.org/api/cell-lines/v1/CVCL_1628/papers?page=2