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Cell line · CVCL_1640

PC-14

Cancer cell line, Homo sapiens. Lung adenocarcinoma. Cellosaurus records it as contaminated. 31 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. PC-14. Cell lines, record CVCL_1640. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1640

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Cell line

As Cellosaurus gives it.

Name
PC-14
Accession
CVCL_1640
RRID
RRID:CVCL_1640
Synonyms
PC 14, PC14
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
45Y
Category
Cancer cell line
Diseases
Lung adenocarcinoma (NCIt C3512)
Derived from
Lymph node (metastatic)
Parent
PC-9 (CVCL_B260)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems2

ProblemCellosaurus's note
ContaminatedShown to be a PC-9 derivative (RCB=RCB0446).
CautionTP53 mutation indicated incorrectly as being at c.742C>T in PubMed=10536175 and PubMed=20557307.

Papers31

PaperJournalYearHow we knowRetractedSource
Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin - albumin fusion.FEBS Open Bio2026Its Methods give the RRID and name the linePubMed
Biogenic Cu/Ni nanotherapeutics from Descurainia sophia (L.) Webb ex Prantl seeds for the treatment of lung cancer.Open Life Sci2025Its Methods give the RRID and name the linePubMed
Spatial Cross-talk Modeling of the Tumor Microenvironment Identifies CCR5-Mediated Glia-to-Glia Signaling as a Key Regulator of Brain Metastatic Progression.Cancer Res2025Its Methods give the RRID and name the linePubMed
Pan-cancer proteomic map of 949 human cell lines.Cancer Cell2022Cellosaurus cites itPubMed
Suppression of non-small-cell lung cancer A549 tumor growth by an mtDNA mutation-targeting pyrrole-imidazole polyamide-triphenylphosphonium and a senolytic drug.Cancer Sci2022Its Methods give the RRID and name the linePubMed
Low-doses of aspirin promote the growth of human PC-9 lung cancer cells through activation of the MAPK family.Exp Ther Med2021Its Methods give the RRID and name the linePubMed
Quantitative Proteomics of the Cancer Cell Line Encyclopedia.Cell2020Cellosaurus cites itPubMed
Radioresistance of KRAS/TP53-mutated lung cancer can be overcome by radiation dose escalation or EGFR tyrosine kinase inhibition in vivo.Int J Cancer2020Its Methods give the RRID and name the linePubMed
Next-generation characterization of the Cancer Cell Line Encyclopedia.Nature2019Cellosaurus cites itPubMed
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.Nature2019Cellosaurus cites itPubMed

1 to 10 of 31

See all 31 papers

Relatives5

RelationCell lineAccessionProblemSource
ParentPC-9CVCL_B260Cell lines
Derived from itPC-14-PM4CVCL_9W69Has a recorded problemCell lines
Derived from itPC14BrCVCL_9W71Has a recorded problemCell lines
Derived from itPC14HMCVCL_J032Has a recorded problemCell lines
Derived from itPC14PE6CVCL_9W70Has a recorded problemCell lines

Cell banks2

Cell bankCatalog numberStatusSource
ECACC90071810ECACC
RCBRCB0446DiscontinuedCellosaurus

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1640

GET https://conductscience.org/api/cell-lines/v1/CVCL_1640/papers?page=2