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Cell line · CVCL_1682

SCC-25

Cancer cell line, Homo sapiens. Tongue squamous cell carcinoma. 71 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. SCC-25. Cell lines, record CVCL_1682. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1682

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Cell line

As Cellosaurus gives it.

Name
SCC-25
Accession
CVCL_1682
RRID
RRID:CVCL_1682
Synonyms
SCC 25, SCC25, hSCC-25
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
70Y
Category
Cancer cell line
Diseases
Tongue squamous cell carcinoma (NCIt C4648); Squamous cell carcinoma of the oral tongue (ORDO Orphanet_457252)
Derived from
Oral cavity, tongue (in situ)
Entry created
2012-04-04
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers71

PaperJournalYearHow we knowRetractedSource
Dual targeting of ACSS2 and ACLY by a novel inhibitor S8588 suppresses oncogenic lipogenesis and overcomes metabolic compensation in oral squamous cell carcinoma.Int J Oral Sci2026Its Methods give the RRID and name the linePubMed
Oral Fungal Infection Impacts Epithelial Innate Immunity to Promote Local and Distal Squamous Cell Carcinoma Progression.Cancer Res2026Its Methods give the RRID and name the linePubMed
Antitumor Activity of Combined Topoisomerase Inhibition and FLASH Radiotherapy in Head and Neck Carcinoma Biomodels.MedComm (2020)2026Its Methods give the RRID and name the linePubMed
Cysteine suppresses the progression of oral squamous cell carcinoma via regulating GLDC.Transl Cancer Res2026Its Methods give the RRID and name the linePubMed
Serum metabolomics profiling in head and neck squamous cell carcinoma: a multicentre diagnostic study.EBioMedicine2026Its Methods give the RRID and name the linePubMed
Newly identified invasion drivers define the tumor front in oral squamous cell carcinoma.Cell Death Discov2026Its Methods give the RRID and name the linePubMed
Maackia amurensis seed lectin inhibits oral squamous cell carcinoma tumorigenesis by suppressing N6-methyladenosine modification-mediated SRY-box transcription factor 2 expression.J Int Med Res2026Its Methods give the RRID and name the linePubMed
Astragaloside IV represses the immune evasion and acidic microenvironment of oral squamous cell carcinoma.Cell Mol Biol Lett2026Its Methods give the RRID and name the linePubMed
Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
The PI3K Inhibitor HCD Promotes Caspase Activation in Head and Neck Squamous Cells by Upregulating the Extrinsic and Intrinsic Apoptosis Pathways.J Oral Pathol Med2026Its Methods give the RRID and name the linePubMed

1 to 10 of 71

See all 71 papers

Relatives6

RelationCell lineAccessionProblemSource
Derived from itEDITGENE SCC-25-Cas9CVCL_F5PICell lines
Derived from itEDITGENE SCC-25-CopGFPCVCL_F5ZFCell lines
Derived from itEDITGENE SCC-25-FLUCCVCL_F5RYCell lines
Derived from itER-SCC-25CVCL_EI28Cell lines
Derived from itHyCyte SCC-25 stable cell line for hSTK3 overexpressionCVCL_F4WDCell lines
Derived from itSCC-25/CPCVCL_A5BQCell lines

Cell banks6

Cell bankCatalog numberStatusSource
ATCCCRL-1628ATCC
BCRC60516BCRC
BCRJ0194BCRJ
CLS300607CLS
DSMZACC-617DSMZ
EDITGENEEDC00069EDITGENE

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1682

GET https://conductscience.org/api/cell-lines/v1/CVCL_1682/papers?page=2

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