Cell line · CVCL_1684
SCC-4
Cancer cell line, Homo sapiens. Tongue squamous cell carcinoma. 43 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. SCC-4. Cell lines, record CVCL_1684. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1684
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Cell line
As Cellosaurus gives it.
- Name
- SCC-4
- Accession
- CVCL_1684
- RRID
- RRID:CVCL_1684
- Synonyms
- SCC 4, SCC4
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 55Y
- Category
- Cancer cell line
- Diseases
- Tongue squamous cell carcinoma (NCIt C4648); Squamous cell carcinoma of the oral tongue (ORDO Orphanet_457252)
- Derived from
- Oral cavity, tongue (in situ)
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers43
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Newly identified invasion drivers define the tumor front in oral squamous cell carcinoma. | Cell Death Discov | 2026 | Its Methods give the RRID and name the line | PubMed | |
| TNFRSF10B, a Therapeutic Target for Oral Squamous Cell Carcinoma Through Integrated Bioinformatics and Preliminary Experiments. | Technol Cancer Res Treat | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target. | Cell Rep Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| T2R5 Agonist Phendione Decreases Cell Viability and Induces Apoptosis in Head and Neck Squamous Cell Carcinoma. | Mol Cancer Ther | 2026 | Its Methods give the RRID and name the line | PubMed | |
| CRB2 Activates an Epigenetic Axis to Promote Ferroptosis in Head and Neck Squamous Cell Carcinoma. | Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells. | Mol Syst Biol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| EGFRvIII-driven microenvironmental fibroblast activation and transformation accelerate oral cancer progression via lipocalin-2/STAT3 axis. | Neoplasia | 2025 | Its Methods give the RRID and name the line | PubMed | |
| ANLN promotes head and neck squamous cell carcinoma progression by upregulating PD-L1 via the ERK-MAPK pathway. | iScience | 2025 | Its Methods give the RRID and name the line | PubMed | |
| SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy. | Mol Oncol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| The deleted in oral cancer (DOC1 aka CDK2AP1) tumor suppressor gene is downregulated in oral squamous cell carcinoma by multiple microRNAs. | Cell Death Dis | 2023 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 43
See all 43 papersRelatives0
None in this release.
Cell banks8
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1684
GET https://conductscience.org/api/cell-lines/v1/CVCL_1684/papers?page=2